Results 71 to 80 of about 58,481 (261)

Assessing the Effect of Adalimumab in Granuloma Annulare: A Case Series and Literature Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Granuloma annulare (GA) is a benign granulomatous skin disorder for which standardized treatment guidelines are lacking due to limited evidence. Adalimumab, a TNF‐α inhibitor, shows promise as a therapeutic option due to its potential to disrupt GA granulomas.
Adriana Caixinha Valorenzos, Line Kibsgaard, Trine Bertelsen   +2 more
wiley   +1 more source

A Randomized, Sham‐Controlled Trial of Repetitive Transcranial Magnetic Stimulation Targeting M1 and S2 in Central Poststroke Pain: A Pilot Trial

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Central poststroke pain (CPSP), a neuropathic pain condition, is difficult to treat. Repetitive transcranial magnetic stimulation (rTMS) targeted to the primary motor cortex (M1) can alleviate the condition, but not all patients respond. We aimed to assess a promising alternative rTMS target, the secondary somatosensory cortex (S2),
Juhani Ojala, Jukka Vanhanen, Hanna Harno, Pantelis Lioumis, Selja Vaalto, Mari A. Kaunisto, Jukka Putaala, Marko Kangasniemi, Erika Kirveskari, Jyrki P. Mäkelä, Eija Kalso   +10 more
wiley   +1 more source

Development and Validation of the Brief Inventory of Treatment Expectations in Chronic Pain (BITEC). [PDF]

Eur J Pain
ABSTRACT Background Expectations shape therapeutic outcomes, yet their systematic assessment remains limited in clinical and research settings. To address this gap, we developed and validated the Brief Instrument for the Assessment of Treatment Expectations in Chronic Pain (BITEC) using Item Response Theory. Methods The study comprised four phases. (I)
Caumo W, França BR, Ehlers J, de Jezus Castro SM, Borges RB, Hirakata VN, Bueno GB, da Torres IL, Fregni F.   +8 more
europepmc   +2 more sources

Melatonin Exerts Chondroprotective Effects Against Osteoarthritis by Promoting PI3K/AKT/FoxO3‐Mediated Mitophagy

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a prevalent degenerative joint disease. This study combines bioinformatics analysis with in vivo and in vitro experiments to elucidate the molecular mechanisms through which melatonin (MT) regulates mitophagy to alleviate OA.
Chao Huang, Gang Zhang, Ying‐Kai Ma, Xin‐Nan Ma, Song‐Cen Lv   +4 more
wiley   +1 more source

Increased Disease Burden in Irritable Bowel Syndrome With Comorbid Conditions and Psychiatric Diagnoses in a Multinational European Cohort: Results From the DISCOvERIE Project. [PDF]

United European Gastroenterol J
ABSTRACT Background Patients with Irritable bowel syndrome (IBS) frequently suffer from comorbid psychiatric or somatic conditions, but the association with overall GI symptom severity and disease burden in IBS has not yet been established. Objective This pan‐European project, the DISCOvERIE project, aimed to characterize IBS patients with and without ...
Midenfjord I, Khadija M, Sundelin E, Trindade IA, Törnblom H, Santos J, Lobo B, Mulder D, Vasquez AA, Ruesing G, Reif A, Aichholzer M, Van Den Houte M, Van Oudenhove L, Matteucci MC, Barbara G, Bosman M, Jonkers D, Ramos-Quiroga JA, Jekkel E, Bitter I, Pop AV, Dumitrascu DL, Alonso-Cotoner C, Rodríguez-Urrutia A, Simrén M.   +25 more
europepmc   +2 more sources

“Zooming” in the association between rosacea and fibromyalgia syndrome: ıs it worth mentioning? [PDF]

, 2023
Sevgi Kulaklı, Işıl Deniz Oğuz, İlker Fatih Sarı, İlker Şengül, Fazıl Kulaklı, Burak Akşan, Demet Şengül   +6 more
openalex   +1 more source

Distinction and mutual Influences between Parkinson's Disease‐related and unrelated Chronic Pain

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Chronic pain (i.e. > 3 months) is a common nonmotor symptom in patients with Parkinson's disease (PD), but the attribution to PD is critical for further treatment. Objectives We explored the PD Pain Classification System (PD‐PCS) criteria for the diagnosis of PD‐related pain and mutual influences between PD‐related and PD‐unrelated ...
Jonathan Hunger, Florian Brugger, Georg Kägi, Jens Carsten Möller, Nathalie Hollenstein, David H. Benninger, Michele Tinazzi, Julien F. Bally, Roman Gonzenbach, Daniel Ciampi de Andrade, Santiago Perez Lloret, Veit Mylius   +11 more
wiley   +1 more source

A Review of NIDDK‐Funded Studies of Urological Chronic Pain Conditions

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction This review highlights NIDDK‐funded clinical research studies focused on interstitial cystitis/bladder pain syndrome (IC/BPS) and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Methods Since 1987, the NIDDK has funded numerous cohort studies, epidemiologic studies, and clinical trials for these conditions.
J. Quentin Clemens
wiley   +1 more source

Elevated Serum Levels of Monocyte Chemotactic Protein-1/Chemokine C-C Motif Ligand 2 are Linked to Disease Severity in Patients with Fibromyalgia Syndrome

Balkan Medical Journal, 2019
Background: Elevated levels of monocyte chemotactic protein-1/chemokine C-C motif ligand 2 have been identified in fibromyalgia patients. Aims: To examine the potential association among serum levels of monocyte chemotactic protein-1/chemokine C-C motif
Yuan-Chuang Zhao, Ting-Hu, Yan-Chen, Ke-Tao Du   +3 more
doaj   +1 more source

How is wakeful rest operationalized and measured in daily life among adults with and without long‐term conditions? A systematic scoping review

PM&R, EarlyView.
Abstract A systematic scoping review was conducted to examine how rest is operationalized and measured in daily life among adults with and without long‐term conditions. Searches were performed in PubMed, Cumulative Index to Nursing and Allied Health Literature, and Psych databases for studies from 1990 to 2024.
Martin Ackah, Katie L. Hackett, Vincent Deary, Florentina Johanna Hettinga, Hosea Boakye, Ulric Sena Abonie   +5 more
wiley   +1 more source