Results 81 to 90 of about 137,271 (365)

Cannabinoids for fibromyalgia [PDF]

Cochrane Database of Systematic Reviews, 2016
This review is one of a series on drugs used to treat fibromyalgia. Fibromyalgia is a clinically well-defined chronic condition of unknown aetiology characterised by chronic widespread pain that often co-exists with sleep problems and fatigue affecting approximately 2% of the general population.
Walitt, Brian, Klose, Petra, Fitzcharles, Mary-Ann, Phillips, Tudor, Häuser, Winfried   +4 more
openaire   +4 more sources

M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy With Comorbid Traits

Advanced Science, EarlyView.
Genes associated with endometriosis risk are highly expressed in M2 macrophages, particularly ligands IL1A and IL1B. Endometrial‐type epithelium and stroma are likely recipients of these ligands. While IL1B treatment disturbs epithelial organization, blockage of the signaling results in a dose‐dependent decrease in spontanesous and evoked pain, reduces
Soledad Ochoa, Fernanda S. Rasquel‐Oliveira, Brett McKinnon, Marcela Haro, Sugarniya Subramaniam, Pak Yu, Simon Coetzee, Michael S. Anglesio, Kelly N. Wright, Raanan Meyer, Anne E. Porter, Caroline E. Gargett, Sally Mortlock, Grant W. Montgomery, Michael S. Rogers, Kate Lawrenson   +15 more
wiley   +1 more source

Tobacco Use in Fibromyalgia Is Associated With Cognitive Dysfunction

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2019
Objective: To evaluate the association between smoking and cognitive function in patients with fibromyalgia. Patients and Methods: We surveyed 668 patients with fibromyalgia from May 1, 2012 through November 30, 2013 at a major tertiary referral center ...
Lin Ge, MD, Ryan S. D'Souza, MD, Terry Oh, MD, Ann Vincent, MD, Arya B. Mohabbat, MD, Jason Eldrige, MD, Li Jiang, MD, Mary O. Whipple, BA, Samantha J. McAllister, BA, Zhen Wang, PhD, Wenchun Qu, MD, MS, PhD, William D. Mauck, MD   +11 more
doaj   +1 more source

FIBROMYALGIA ONSET

The American Journal of Nursing, 2000
Michele de Jesus
openalex   +3 more sources

Diagnosis, Prognosis, and Drug Target Discovery for Chronic Widespread Pain: A Large Proteogenomic Study

Advanced Science, EarlyView.
Plasma proteomics is leveraged to decode the biological underpinnings of chronic widespread pain. A nested machine learning framework integrates proteomic signatures, prospective outcomes, and Mendelian randomization to uncover 18 causal proteins.
Li Chen, Eoin Kelleher, Ruogu Meng, Duanke Liu, Yuchen Guo, Yunhe Wang, Yaqing Gao, Zhe Huang, Zhu Liang, Shuai Yuan, Chao Zeng, Jun Ma, Yanhui Dong, Anushka Irani, Guanghua Lei, Junqing Xie, Daniel Prieto‐Alhambra   +16 more
wiley   +1 more source

Parvovirus B19 Infection as a Potential Trigger for Systemic Diseases. [PDF]

Clin Case Rep
ABSTRACT It is crucial to perform direct methods like polymerase chain reaction (PCR) beyond serology to diagnose an active viral infection that can trigger a cutaneous/systemic disease, such as fibromyalgia. Indeed, measuring the viral load in tissues, plasma, and serum are diagnostic tools that permit the follow‐up of an active infection.
Ciccarese G, Varesano S, Serviddio G, Drago F.   +3 more
europepmc   +2 more sources

Fibromyalgia and Depression [PDF]

Pain Research and Treatment, 2012
Fibromyalgia and depression might represent two manifestations of affective spectrum disorder. They share similar pathophysiology and are largely targeted by the same drugs with dual action on serotoninergic and noradrenergic systems. Here, we review evidence for genetic and environmental factors that predispose, precipitate, and perpetuate ...
Richard H. Gracely, Marta Ceko, M. Catherine Bushnell   +2 more
openaire   +3 more sources

μ‐Opioid Receptor Dynamics in the Parameningeal Tissue During Migraine Attacks

Annals of Neurology, EarlyView.
Objective The possible impact of meningeal μ‐opioid receptor (μOR) binding in migraine remains unknown. This study investigated μOR availability in the cranial parameninges involved in migraine initiation via nociceptor activation. Methods We used positron emission tomography with [11C] carfentanil, and measured μOR availability in meninges and ...
Dajung J. Kim, Manyoel Lim, Thiago D. Nascimento, Frank Porreca, Robert A. Koeppe, Nouchine Hadjikhani, Alexandre F. DaSilva   +6 more
wiley   +1 more source

Associations Between Changes in Pain Sensitization and Disease Activity Following Disease‐Modifying Antirheumatic Drug Therapy in Established Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Abnormalities in pain regulatory mechanisms are common in patients with rheumatoid arthritis (RA). We investigated whether pain sensitization changes after treatment with a disease‐modifying antirheumatic drug (DMARD) and explored associations between changes in pain sensitization and disease activity.
Burcu Aydemir, Andrew C. Heisler, Lutfiyya N. Muhammad, Jing Song, Alyssa Wohlfahrt, Daniel J. Clauw, Wendy Marder, Marcy B. Bolster, Clifton O. Bingham, Tuhina Neogi, Yvonne C. Lee   +10 more
wiley   +1 more source

Rehabilitation Interventions Delivered via Telehealth to Support Self‐Management of Rheumatic and Musculoskeletal Disease: A Scoping Review

Arthritis &Rheumatology, EarlyView.
Objective To identify and summarize existing telerehabilitation interventions for people living with rheumatic and musculoskeletal diseases (RMDs), including the rehabilitation components, the technology used, the type of health care professional (HCP) interaction, and how the effectiveness is evaluated.
Thomas A. Ingram, Rosemarie Barnett, Nuzhat Shakaib, Simon Jones, Raj Sengupta, Peter C. Rouse   +5 more
wiley   +1 more source