Results 261 to 270 of about 354,159 (381)

RSPO2 Coordinates with GDF9:BMP15 Heterodimers to Promote Granulosa Cell and Oocyte Development in Mice

open access: yesAdvanced Science, EarlyView.
RSPO2 and GDF9:BMP15 heterodimers—core components of oocyte‐secreted factors (OSFs)—coordinate to shape the molecular architecture of preantral granulosa cells via gene‐specific synergistic and antagonistic regulation, mediated through CTNNB1–SMAD2 signaling crosstalk.
Yingmei Wang   +7 more
wiley   +1 more source

Inhibition of epigenetic regulator UHRF1 attenuates renal fibrosis and retains transcription factor Krüppel-like factor 15 expression. [PDF]

open access: yesCell Death Discov
Gu Y   +11 more
europepmc   +1 more source

The GRK2/AP‐1 Signaling Axis Mediates Vascular Endothelial Dysfunction and Atherosclerosis Induced by Oscillatory Low Shear Stress

open access: yesAdvanced Science, EarlyView.
This study highlights GRK2 is a central mediator in OSS‐induced endothelial dysfunction. OSS activates GPCRs in endothelial cells, leading to GRK2 phosphorylation and the activation of AP‐1. AP‐1 induces inflammation, while also promoting NR4A1 expression and anchoring LKB1 in the nucleus, which suppresses AMPK activity. This cascade causes endothelial
Li‐Da Wu   +18 more
wiley   +1 more source

Hydrodynamically generated multilayer skin spheroids enable in vitro screening of biologically active ingredients and toxicity tests. [PDF]

open access: yesSci Adv
Chen Z   +8 more
europepmc   +1 more source

Chromosomal localization of the genes for the vitronectin and fibronectin receptors alpha subunits and for platelet glycoproteins IIb and IIIa.

open access: bronze, 1988
Donna M. Sosnoski   +9 more
openalex   +1 more source

Bionic Nanostructures Create Mechanical Signals to Mediate the Composite Structural Bone Regeneration Through Multi‐System Regulation

open access: yesAdvanced Science, EarlyView.
Inspired by the structural and functional characteristics of bone, bionic nanomaterials combined with nanotechnology can more accurately replicate stem cell niches, enabling the design of bone tissue engineering scaffolds with diverse nanoscale properties to promote stem cell migration, proliferation, and differentiation. This precise control over stem
Yangfan Pei   +11 more
wiley   +1 more source

Fibronectin Receptor Function

open access: yesJournal of Investigative Dermatology, 1986
Stephanie P. Alstadt   +1 more
openaire   +3 more sources

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