Results 281 to 290 of about 343,520 (320)

Single‐Cell Morphomechanics of Prostate Cancer‐Associated Fibroblasts Identifies Distinct Features Associated with Patient Outcome

Advanced Science, EarlyView.
Cancer‐associated fibroblasts (CAFs) in prostate tumors exhibit distinct morphomechanical traits vs normal fibroblasts, including greater stiffness and volume, more elongated stress fibres, and larger and more elongated nuclei. These features, quantified through imaging and real‐time deformability cytometry, correlate with patient outcomes and can be ...
Antje Garside, Angela Jacobi, Shivakumar Keerthikumar, Vaibhav Mahajan, Michelle Richards, Birunthi Niranjan, Linda Teng, Nicholas Choo, Johannes Low Jun Wei, Gail P Risbridger, Mitchell G Lawrence, Anna V. Taubenberger   +11 more
wiley   +1 more source

Immunofluorescence staining profiles of glomerular diseases: a single-center retrospective study. [PDF]

Biochem Biophys Rep
Song J, Cui X, Yuan S, Liu H, Liu Y, Zhou X, Sun L, Zhu X, Li Y.   +8 more
europepmc   +1 more source

Jointless Tongue‐Like Bioactuator for Multidirectional Motion Through Directional Electrical Stimulation

Advanced Intelligent Systems, EarlyView.
A tongue‐like bioactuator is developed using orthogonally aligned cultured skeletal muscle tissues. By applying directional electrical stimulation of varying strengths, the actuator achieves jointless, multidirectional movements. The device features a fully soft, skeleton‐free design, enabling biomimetic deformation and functional actuation, and offers
Xuankai Gao, Kouhei Okasaki, Hirono Ohashi, Takeshi Sakurai, Yuya Morimoto   +4 more
wiley   +1 more source

Effect of 2D and 3D ECM and Biomechanical Cues on Human iPSC-Derived Liver Progenitor Cell Differentiation. [PDF]

Adv Healthc Mater
Jain I, Grenci B, Ryoo H, Yuan Y, Khetani SR, Underhill GH.   +5 more
europepmc   +1 more source

Recent advances in animal models for pathological scar research: A comprehensive review of experimental approaches and translational relevance

Animal Models and Experimental Medicine, EarlyView.
Animal models remain indispensable in the study of pathological scars, each offering unique advantages and constraints. Their integration with in vitro and ex vivo systems is key to developing personalized, clinically translatable antifibrotic therapies. Abstract Pathological scarring, manifested in the form of hypertrophic scars (HTS) and keloid scars
Diana‐Larisa Ancuța, Mariana Văduva, Cristin Coman, Iuliana Caraș   +3 more
wiley   +1 more source

Heterotypic 3D Model of Breast Cancer Based on Tumor, Stromal and Endothelial Cells: Cytokines Interaction in the Tumor Microenvironment. [PDF]

Cells
Leonteva A, Kazakova A, Berezutskaya E, Ilyina A, Sergeevichev D, Vladimirov S, Bogachek M, Vakhrushev I, Makarevich P, Richter V, Nushtaeva A.   +10 more
europepmc   +1 more source

The Effects of PAK-Regulated Tumour Vasculature on Gemcitabine Response of Pancreatic Cancer. [PDF]

Cancers (Basel)
Ansardamavandi A, Dumesny C, Ma Y, Dong L, Ellis S, Ang CS, Nikfarjam M, He H.   +7 more
europepmc   +1 more source

Preparation of Vitrified Mammalian Cells for In Situ Cryo-Electron Tomography. [PDF]

Curr Protoc
Martin-Solana E, Frendi S, Ning J, Banks-Tibbs T, Vockley J, Freyberg Z.   +5 more
europepmc   +1 more source

The novel circular RNA circG6pc attenuates oxidative stress and mitochondrial damage through miR-7018-5p/Aldh6a1 axis in kidney fibrosis. [PDF]

Cell Mol Biol Lett
Zhao X, Xiong Y, Qin X, Hu J, Huang S, Ni X, Jian J, Yang S, Weng X, Chen H, Chen Z, Liu X, Wang L.   +12 more
europepmc   +1 more source