Results 291 to 300 of about 354,159 (381)

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1992
S. Hanks   +3 more
semanticscholar   +1 more source

Lysosome‐Featured Cell Aggregate‐Released Extracellular Vesicles Regulate Iron Homeostasis and Alleviate Post‐Irradiation Endothelial Ferroptosis for Mandibular Regeneration

open access: yesAdvanced Science, EarlyView.
Lysosomal redistribution occurs via extracellular vesicles in multi‐stem cell aggregates and controls iron homeostasis for safeguarding cell aggregation. These cell aggregate‐released extracellular vesicles (CA‐EVs) rescue lysosomal impairments and exert anti‐ferroptosis effects in recipient irradiated endothelial cells.
Yuan‐Yuan Li   +20 more
wiley   +1 more source

Large‐Scale Bioprinting of Human Epiblast‐Like Models Featuring Disc‐Shaped Morphogenesis and Gastrulation Events

open access: yesAdvanced Science, EarlyView.
Large‐scale generation of disc‐shaped models mimicking human epiblast layer is achieved by bioprinting of human pluripotent stem cells using a well‐defined biomatrix. The bioactive component and physical confinement from laminin/alginate microgels, combined with the endogenous regulation of the WNT signaling pathway regulated disc‐like morphogenesis ...
Yixue Luo   +11 more
wiley   +1 more source

A Novel Interaction of Staphylococcal Protein A With Human Fibronectin and Its Implications in Host Cell Adhesion. [PDF]

open access: yesFASEB J
Camaione S   +12 more
europepmc   +1 more source

Circulating Tumor Cells Shed Shearosome Extracellular Vesicles in Capillary Bifurcations That Activate Endothelial and Immune Cells

open access: yesAdvanced Science, EarlyView.
Using microfluidic models of capillary networks, this study discovered that fluid shear stresses on circulating tumor cells transiting through capillary‐sized bifurcations shed a novel class of shear‐dependent large extracellular vesicle, “shearosomes”, whose proteome comprises of over 3000 distinct proteins.
Angelos Vrynas   +16 more
wiley   +1 more source

Spatiotemporal Adaptations‐Driven Dynamic Thra Activation Simulates a Skin Wound Healing Response

open access: yesAdvanced Science, EarlyView.
This study uncovers the thyroid hormone receptor Thra as a pivotal regulator that spatiotemporally orchestrates dual‐phase skin repair. Epidermal Thra accelerates barrier restoration via glutathione‐driven keratin assembly, while dermal Thra establishes angiogenic niches through SAA3‐FN1‐mediated matrix remodeling.
Zeming Li   +15 more
wiley   +1 more source

In vitro studies of human erythropoiesis using a 3D silk-based bone marrow model that generates erythroblastic islands. [PDF]

open access: yesBlood Adv
Di Buduo CA   +16 more
europepmc   +1 more source

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