Plasma proteins and coronary atherosclerosis: A Mendelian randomization study. [PDF]
Pan H+5 more
europepmc +1 more source
ABSTRACT Protein developability is an important, yet often overlooked, aspect of protein discovery campaigns that is a key driver of utility. Recent advances have improved developability screening capacity, making it an increasingly viable option in early‐stage discovery.
Gregory H. Nielsen+2 more
wiley +1 more source
Comparison of glycosylated fibronectin versus soluble fms-like tyrosine kinase/placental growth factor ratio testing for the assessment of pre-eclampsia: protocol for a multicentre diagnostic test accuracy study. [PDF]
Elbarbary N+6 more
europepmc +1 more source
Recent advances of nanomaterials in imaging liver fibrosis
Schematic summary on the latest strategies of liver fibrosis imaging based on various nanomaterials. Abstract Liver fibrosis is a pathological process resulting from prolonged exposure to various injury factors. It is characterized by the abnormal proliferation and activation of hepatic stellate cells and excessive deposition of extracellular matrix ...
Jin Cui+11 more
wiley +1 more source
Mechanistic role of FN1 in LAIR-1 mediated downregulation of ovarian cancer cell proliferation. [PDF]
Zhang H+10 more
europepmc +1 more source
Engineering antibodies with cancer‐associated binding sites
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian+4 more
wiley +1 more source
Menopause mysteries: the exosome-inflammation connection. [PDF]
Sultania A+4 more
europepmc +1 more source
Deciphering the skeletal interoceptive circuitry to control bone homeostasis
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu+7 more
wiley +1 more source
A novel serum protein biomarker for the late-stage diagnosis of nasopharyngeal carcinoma. [PDF]
Pan YX, Huang Q, Xing S, Zhu QY.
europepmc +1 more source
Artificial intelligence‐assisted design, synthesis and analysis of smart biomaterials
Smart biomaterials are rapidly emerging as tools for tissue engineering, and artificial intelligence has played essential roles in biomaterial studies. By bridging the literature gap in AI‐based design, synthesis and analysis of smart biomaterials, the current review shares perspectives on how biomaterial scientists can practically incorporate AI for ...
Pengfei Jiang+9 more
wiley +1 more source