Results 171 to 180 of about 86,137 (348)

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

HuR-Targeted Small Molecules Reduce <i>Pseudomonas aeruginosa</i> Adhesion in Cystic Fibrosis Airway Epithelial Cells. [PDF]

Int J Mol Sci
Listro R, Pellegrini A, Rossino G, Linciano P, Pietrocola G, Collina S.   +5 more
europepmc   +1 more source

Fibrinogen controls human platelet fibronectin internalization and cell‐surface retention [PDF]

, 2007
Zhimin Zhai, Jiali Wu, Xiaojun Xu, Kaiyang Ding, Ran Ni, Wen Hu, Zimin Sun, Heyu Ni   +7 more
openalex   +1 more source

RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy

Advanced Science, EarlyView.
This study revealed a novel role of the chemokine‐TGF‐β1‐RUNX2 axis in determining the fate of FAP differentiation and modulating muscle fibrosis in patients and mice with muscular dystrophies. ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying ...
Pengkai Wu, Zehua Zhang, Kai Zheng, Ziqi Zhu, Yong Zhu, Abdukahar Kiram, Lei Zhao, Huihui Chen, Zhu Xu, Xihua Li, Beicheng Sun, Zhijian Li, Dengqiu Xu   +12 more
wiley   +1 more source

Exploring irisin levels in patients with endometrial atypical hyperplasia and carcinoma: a comparative analysis. [PDF]

BMC Cancer
Bildacı TB, Ata C, Atlıhan U, Avsar HA, Erkılınc S.   +4 more
europepmc   +1 more source

Electron microscopy and structural model of human fibronectin receptor.

, 1988
M. V. Nermut, N. M. Green, P. Eason, Sadako Yamada, Kenneth M. Yamada   +4 more
openalex   +2 more sources

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

Current knowledge and scientific trends in myokines and exercise research in the context of obesity. [PDF]

Front Med (Lausanne)
Letukienė A, Hendrixson V, Ginevičienė V.   +2 more
europepmc   +1 more source

Localization of the Domains of the Haemophilus ducreyi Trimeric Autotransporter DsrA Involved in Serum Resistance and Binding to the Extracellular Matrix Proteins Fibronectin and Vitronectin

, 2008
Isabelle Leduc, Bonnie Olsen, Christopher A. Elkins   +2 more
openalex   +2 more sources

The oncofetal domain of fibronectin defined by monoclonal antibody FDC-6: its presence in fibronectins from fetal and tumor tissues and its absence in those from normal adult tissues and plasma.

Proceedings of the National Academy of Sciences of the United States of America, 1985
H. Matsuura, S. Hakomori
semanticscholar   +1 more source