Results 81 to 90 of about 94,496 (352)

A positive feedback loop driven by fibronectin and IL-1β sustains the inflammatory microenvironment in breast cancer [PDF]

, 2023
Gürcan Tunalı, Hamdullah Yanık, Süleyman Can Öztürk, Seçil Demirkol Canlı, Georgios Efthymiou, Kerim Bora Yılmaz, Ellen Van Obberghen‐Schilling, Güneş Esendağlı   +7 more
openalex   +1 more source

Cardiac‐Derived ECM Microspheres for Enhanced hiPSC‐CMs Maturation

Advanced Functional Materials, EarlyView.
Cardiac extracellular matrix microspheres derived from decellularized porcine heart provide a biomimetic 3D microenvironment for human induced pluripotent stem cell–derived cardiomyocytes (hiPSC‐CMs). This platform supports short‐ and long‐term culture, enhances structural organization, and promotes electrophysiological and functional maturation of ...
Jiazhu Xu, Joel Aboagye, Marcella Edwards, Nick Rogozinski, Yufeng Wen, Angello Huerta Gomez, Zui Pan, Ge Zhang, Huaxiao Yang, Yi Hong   +9 more
wiley   +1 more source

Towards definition of an ECM parts list: An advance on GO categories [PDF]

, 2012
Those of us interested in the extracellular matrix (ECM) are faced with significant challenges of definition. ECM proteins are large, complex and assembled into crosslinked insoluble matrices.
Hoersch, Sebastian, Hynes, Richard O., Hynes, Richard O., Naba, Alexandra   +3 more
core   +1 more source

Mechanoregulatory Effects of Cell‐Scale Microwells on Epithelial Cell Phenotype

Advanced Functional Materials, EarlyView.
In small polycaprolactone microwells, A549 epithelial cells span well edges, in contrast to cells growing on flat substrates. Focal adhesion sites (yellow) concentrate at topographic boundaries, while cytoskeletal tension (magenta stress fibers) is transmitted to the nucleus (blue), reducing nuclear sphericity.
Ruiwen He, Wang Sik Lee, Phattadon Yajan, Aaron Lee, Mauro Sousa de Almeida, Sandeep Keshavan, Jozef Adamcik, Céline Loussert‐Fonta, Dimitri Vanhecke, Barbara Rothen‐Rutishauser, Alke Petri‐Fink   +10 more
wiley   +1 more source

In silico analysis and functional characterization of a leucine-rich repeat protein of Leptospira interrogans

International Journal of Medical Microbiology
Pathogenic spirochetes of the genus Leptospira are the causative agent of leptospirosis, a widely disseminated zoonosis that affects humans and animals.
João P. Gaspar, Maria B. Takahashi, Aline F. Teixeira, Ana L.T.O. Nascimento   +3 more
doaj   +1 more source

Microfluidic Platform for Multiparametric Profiling of Fibrin Permeability, Fibrinolysis, and Cell Invasion

Advanced Functional Materials, EarlyView.
This paper introduces a single‐channel H‐junction microfluidic assay that profiles fibrin's evolving function in repair and thrombosis by measuring, in one ∼3 µL gel, permeability, fibrinolysis kinetics, fibroblast invasion, and clot extension in real time.
Halston Deal, Elizabeth M. Byrnes, Sanika Pandit, Halle J. Cantor, Muskan Aslam, Stacy Ban, Megan Palmisano, Rosemary Bayless, Ashley C. Brown, Michael Daniele   +9 more
wiley   +1 more source

Virulence factors of Candida albicans strains

One Health & Risk Management, 2023
Introduction. Candida albicans is a common commensal fungus that colonizes the oropharyngeal cavity, gastrointestinal and vaginal tract, and healthy individuals’ skin. In 50% of the population, C.
Cristian IAZAJII
doaj  

The alternatively spliced V region contributes to the differential incorporation of plasma and cellular fibronectins into fibrin clots

Journal of Cell Biology, 1992
During blood clot formation in vivo, plasma fibronectin (pFN) is cross- linked to fibrin by coagulation factor XIIIa. Cellular FN (cFN), which localizes to connective tissue, is distinguished from pFN by the inclusion of alternatively spliced segments ...
Carole L. Wilson, J. Schwarzbauer
semanticscholar   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Studies of extracellular fibronectin matrix formation with fluoresceinated fibronectin and fibronectin fragments

FEBS Letters, 1985
Fluorescein isothiocyanate conjugated human plasma fibronectin, 70‐kDa collagen‐binding, 60‐kDa central, 60‐kDa heparin‐binding, 180‐kDa heparin, collagen‐binding fibronectin fragments and gelatin were used to study extracellular fibronectin matrix formation.
Chernousov, M.A., Metsis, M.L., Koteliansky, V.E.   +2 more
openaire   +2 more sources