Results 211 to 220 of about 1,274,104 (305)

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

Advanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min, Nam Than, Yong Cheol Shin, Elif G. Ertugral, Chandrasekhar R. Kothapalli, Olumuyiwa Awoniyi, Hyun Jung Kim   +6 more
wiley   +1 more source

Mesenteric and antimesenteric border subregionalization using MR enterography: advancing fibrosis evaluation in Crohn disease. [PDF]

Eur Radiol Exp
Wu L, Lin J, Zheng W, Zhang R, Zheng Q, Wang Y, Ke Y, Ye Z, Liu X, Li Z, Mao R, Peng Z, Sun C, Chen Z, Feng ST, Huang L, Shen X, Li X.   +17 more
europepmc   +1 more source

Retroperitoneal Fibrosis

Journal of Osteopathic Medicine, 2017
Jennifer, Conard, Michelino, Mancini
openaire   +2 more sources

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

Advanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen, Zixing Xu, Zerun Hao, Yanming Chen, Kai Xie, Haofan Yin, Xueying Wang, Jie Min, Sihan Sun, Baiding Chen, Chengxiu Ling, Mingming Xu, Yizhao Chen, Gang Ruan   +13 more
wiley   +1 more source

A multicentre survey of liver fibrosis burden in type 2 diabetes in India: the DiaFib-Liver Study. [PDF]

Lancet Reg Health Southeast Asia
Kumar A, Panda JK, Agrawal P, Gupta S, Kumar D, Kuchay MS, Kesavadev J, Mohan V, Jagadeesha A, Saboo B, Tewari A, Das K, Chandra KP, Kulkarni SV, Patil S, Gupta A, Goswami P, Hasnani D, Chavda V, Agrawal M, Chhaya G, Muralidharan C, Kannan A, Rana P, Rastogi A, Biradar S, Agasti K, Sankar P, Murthy LS, Suvarna D, Kapoor R, Shah K, Gupta M, Suri S, Srivastava A, Sanyal D, Bagri S, Gupta VK, Sowani A, Chawla P, S MH, Banthia NM, Farishta F, Kapoor S, Husaini SHM, Sharma P, Arora A, Misra A.   +47 more
europepmc   +1 more source

Radical‐Mediated, Substrate‐Independent Fabrication of Hybrid Solid–Hydrogel Materials With Tunable Crosslinking: An Initiator‐ and Crosslinker‐Free Approach

Advanced Science, EarlyView.
This work introduces a substrate‐independent, reagent‐free plasma strategy that forms radical‐rich interlayers for covalent hydrogel attachment without initiators or crosslinkers. The long‐lived radicals drive in situ gelation, creating robust, cytocompatible hybrid solid–hydrogel constructs across diverse substrates.
Ghazal Shineh, Azin Khodaei, Pardis Keikhosravani, Masoud Zhianmanesh, Yiyun Xia, Aaron Gilmour, Sina Naficy, Andrea Guzina, Daniella Bianchi, Khoon S. Lim, Fariba Dehghani, Saber Amin Yavari, Marcela Bilek, Giselle C. Yeo, Behnam Akhavan   +14 more
wiley   +1 more source

Care Pathways for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A State-of-The-Art Review. [PDF]

Liver Int
van Eekhout KMA, Broekman LD, de Jong VD, Michel M, Grobbee R, Maya-Miles D, Romero-Gómez M, Muris J, Mendive JM, Vali Y, Franco OH, Schattenberg JM, Fournier-Poizat C, Castro Cabezas M, Tushuizen ME, Holleboom AG, GRIPonMASH consortium.   +16 more
europepmc   +1 more source

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

Advanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen, Hao Shi, Junxian He, Ziyu Liu, Yuanyuan Zhu, Xiaoyan Liang, Guihua Liu, Xing Yang   +7 more
wiley   +1 more source

Fibrosis-memory is mediated by IL-3-producing T cells and drives progression of fibrosis. [PDF]

J Clin Invest
Buchtler S, Frühauf A, Neumayer S, Schmidbauer K, Talke Y, Winter-Köhler F, Balam S, Landgraf K, Gebhard C, Rehli M, Schlieckau FV, Beck M, Günther F, Fleck M, Renner K, Mack M.   +15 more
europepmc   +1 more source