The gut microbiome is a potential target for treating cardiovascular disease. It is found that prophylactic administration of Flavonifractor plautii or its metabolite desaminotyrosine (DAT) exerts pleiotropic cardioprotective effects via promoting cardiomyocyte survival and attenuating cardiac inflammation against myocardial ischemia/reperfusion (I/R ...
Heng Du+21 more
wiley +1 more source
Identification of early genes in the pathophysiology of fibrotic interstitial lung disease in a new model of pulmonary fibrosis. [PDF]
Hennion N+7 more
europepmc +1 more source
A unique hydrogel based on extracellular matrix from fish swim bladder, which is suitable for transcatheter delivery and possesses remarkable reparative capabilities for treating heart failure, is developed. It emerges as a multi‐effect factor profoundly influencing inflammation regulation, angiogenesis, and myocardial metabolism.
Yulong Fu+9 more
wiley +1 more source
Neural network analysis as a novel skin outcome in a trial of belumosudil in patients with systemic sclerosis. [PDF]
Gunes I+19 more
europepmc +1 more source
Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequencing. [PDF]
Peng Y+6 more
europepmc +1 more source
Inhibition of Transglutaminase 2 by a Selective Small Molecule Inhibitor Reduces Fibrosis and Improves Pulmonary Function in a Bleomycin Mouse Model. [PDF]
Wang Z+5 more
europepmc +1 more source
Chikusetsusaponin IVa targeted YAP as an inhibitor to attenuate liver fibrosis and hepatic stellate cell activation. [PDF]
Gao K+6 more
europepmc +1 more source
Prediction of major liver-related events in the population using prognostic models. [PDF]
Åberg F, Männistö V.
europepmc +1 more source