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Liver fibrosis

Springer Seminars in Immunopathology, 1999
Knowledge on the development and progression of liver fibrosis has grown exponentially in the past decade. At present, liver fibrogenesis is referred to as a dynamic process involving complex cellular and molecular mechanisms, resulting from the chronic activation of the tissue repair mechanisms that follows reiterated liver tissue injury.
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The pathogenesis of pulmonary fibrosis: Is there a fibrosis gene?

The International Journal of Biochemistry & Cell Biology, 1997
Interstitial fibrosis is seen in the lung in response to a variety of insults, and often appears stereotypical in terms of its clinical and pathological features. However, exposure to a known aetiological factor does not always lead to fibrosis. For example in bleomycin-induced pulmonary fibrosis, a wide variation in response is seen both in humans and
Geoffrey J. Laurent   +2 more
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Retroperitoneal fibrosis

Urologic Radiology, 1990
Retroperitoneal fibrosis is idiopathic in two thirds of cases and is found most commonly as an isolated fibrotic plaque centered over the lower lumbar spine and entrapping one or both ureters. It has been postulated that the fibrosis in the idiopathic cases results from a hypersensitivity reaction to antigens leaking into the retroperitoneum from ...
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Cystic fibrosis

Current Opinion in Pulmonary Medicine, 2003
On a daily basis, pathologists examine the fundamental basis of human diseases using morphologic, immunologic, and molecular techniques. Cystic fibrosis (CF), as a clinically heterogeneous disease, exemplifies the complex challenges of genetic diseases for the pathologist who attempts to explain the mechanisms of disease and provide rationale for ...
Myra J, Lewis   +3 more
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Fibrosis and angiogenesis

Current Opinion in Nephrology and Hypertension, 2000
Research during the past few years has contributed vastly to a better understanding of fibrosis and angiogenesis. Although studies to understand the molecular processes associated with fibrosis and angiogenesis were performed independently of each other, some common parallels have emerged.
Vikas P. Sukhatme, Raghu Kalluri
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Fibrosis in scleroderma

Rheumatic Disease Clinics of North America, 2003
The pathogenesis of fibrosis in scleroderma involves a complex set of interactions between the fibroblast and its surroundings. Multiple fibrotic pathways are activated for reasons that are not completely clear, but involve immune activation, microvascular damage, and fibroblast transformation into the myofibroblast.
Eugene Y. Kissin, Joseph H. Korn
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An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline: Treatment of Idiopathic Pulmonary Fibrosis. An Update of the 2011 Clinical Practice Guideline.

American Journal of Respiratory and Critical Care Medicine, 2015
BACKGROUND This document updates the American Thoracic Society/European Respiratory Society/Japanese Respiratory Society/Latin American Thoracic Association guideline on idiopathic pulmonary fibrosis treatment.
G. Raghu   +20 more
semanticscholar   +1 more source

Cystic fibrosis

Current Problems in Pediatrics, 1993
The past few years have seen amazing progress in our understanding of the underlying cellular and molecular bases of CF. This new understanding has raised hopes for improved treatments in the very near future. These new treatments are expected to improve even further the prognosis for survival in this disorder, which has improved nearly 1 year for ...
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Idiopathic Pulmonary Fibrosis.

New England Journal of Medicine, 2018
Idiopathic Pulmonary Fibrosis Idiopathic pulmonary fibrosis appears to be increasing in incidence. It requires early recognition and intervention with supportive care and pharmacologic agents to forestall its progression.
D. Lederer, F. Martinez
semanticscholar   +1 more source

Cystic fibrosis

Current Opinion in Infectious Diseases, 2002
Cystic fibrosis is the most common lethal inherited disorder with autosomal recessive inheritance. Major progress has been made in understanding the molecular mechanisms leading to increased susceptibility to Pseudomonas aeruginosa colonization. Persistent respiratory infection with P.
Amanda L, Brennan, Duncan M, Geddes
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