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Cystic fibrosis

Current Problems in Pediatrics, 1993
The past few years have seen amazing progress in our understanding of the underlying cellular and molecular bases of CF. This new understanding has raised hopes for improved treatments in the very near future. These new treatments are expected to improve even further the prognosis for survival in this disorder, which has improved nearly 1 year for ...
openaire   +2 more sources

Fibrosis with emphysema

Histopathology, 2010
Wright J L, Tazelaar H D & Churg A (2011) Histopathology 58, 517–524
Fibrosis with emphysemaThe concept of fibrosis with emphysema is confused by the existence of two very different clinical/pathological scenarios: first, cases in which a diffuse fibrosing interstitial pneumonia, most commonly usual interstitial pneumonia (UIP), occurs in a patient
Joanne L. Wright   +2 more
openaire   +3 more sources

Fibrosis in scleroderma

Rheumatic Disease Clinics of North America, 2003
The pathogenesis of fibrosis in scleroderma involves a complex set of interactions between the fibroblast and its surroundings. Multiple fibrotic pathways are activated for reasons that are not completely clear, but involve immune activation, microvascular damage, and fibroblast transformation into the myofibroblast.
Eugene Y. Kissin, Joseph H. Korn
openaire   +3 more sources

Cystic fibrosis

Current Opinion in Infectious Diseases, 2002
Cystic fibrosis is the most common lethal inherited disorder with autosomal recessive inheritance. Major progress has been made in understanding the molecular mechanisms leading to increased susceptibility to Pseudomonas aeruginosa colonization. Persistent respiratory infection with P.
Amanda L, Brennan, Duncan M, Geddes
openaire   +2 more sources

An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline: Treatment of Idiopathic Pulmonary Fibrosis. An Update of the 2011 Clinical Practice Guideline.

American Journal of Respiratory and Critical Care Medicine, 2015
BACKGROUND This document updates the American Thoracic Society/European Respiratory Society/Japanese Respiratory Society/Latin American Thoracic Association guideline on idiopathic pulmonary fibrosis treatment.
G. Raghu   +20 more
semanticscholar   +1 more source

Molecular and cellular mechanisms of liver fibrosis and its regression

Nature reviews: Gastroenterology & hepatology, 2020
T. Kisseleva, D. Brenner
semanticscholar   +1 more source

Cystic Fibrosis

Journal of the Iowa Medical Society, 2009
John McArdle1, Laurie Whittaker2
semanticscholar   +1 more source

Epigenetics in fibrosis

Molecular Aspects of Medicine, 2017
Fibrosis is a common and important disease. It is a pathological state due to excessive scar formation mediated by an increase in activated fibroblasts that express alpha smooth muscle actin and copious amounts of extracellular matrix molecules.
openaire   +2 more sources

TGF-β: the master regulator of fibrosis

Nature Reviews Nephrology, 2016
Xiao-ming Meng   +2 more
semanticscholar   +1 more source

Fibrosis: A General Feature in Cystic Fibrosis?

Journal of Pediatric Gastroenterology and Nutrition, 2002
G. Heimann   +2 more
openaire   +3 more sources

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