Results 41 to 50 of about 291,194 (118)

Capillaria hepatica in rats: focal parasitic hepatic lesions and septal fibrosis run independent courses

Memorias do Instituto Oswaldo Cruz, 2006
Capillaria hepatica causes two main lesions in the liver of rats: multifocal chronic inflammation, directly related to the presence of disintegrating parasites and their eggs, and a process of systematized septal fibrosis.
Ana Thereza Gomes, Liliane Monteiro Cunha, Carla Guimarães Bastos, Bruno Frederico Medrado, Bárbara CA Assis, Zilton A Andrade   +5 more
doaj   +1 more source

Revisiting Ferritin‐IgG Score to Predict Complete Biochemical Response in Autoimmune Hepatitis

Alimentary Pharmacology &Therapeutics, EarlyView.
The ferritin‐IgG score failed external validation in a large Spanish multicentre cohort. However, baseline IgG ≥ 1.89×ULN independently predicted both complete biochemical response and biochemical response (defined as transaminase normalization), identifying patients less likely to achieve timely remission with standard therapy.
Álvaro Díaz‐González, Bastian Engel, Manuel Hernández‐Guerra, Indhira Pérez‐Medrano, Beatriz Mateos, Rosa M. Morillas, Elena Gómez, Judith Gómez, Diana Horta, Isabel Conde, María Del Barrio, Ignasi Olivas, Ismael El Hajra, Mar Riveiro‐Barciela, Ana Barreira‐Díaz, Carmen López, Carmen Álvarez‐Navascúes, Manuel Rodríguez Perálvarez, Elmar Jaeckel, Richard Taubert, María‐Carlota Londoño   +20 more
wiley   +1 more source

Comparative evaluation of APRI, FIB-4, HFS, and NFS: Scoring tools for liver fibrosis in a Mexican population with MASLD

Revista de Gastroenterología de México (English Edition)
Introduction and aim: Liver fibrosis is a complication of metabolic dysfunction-associated steatotic liver disease (MASLD). Given the limitations and risks of liver biopsy, examining noninvasive scoring systems that are affordable for the population is ...
B.A. Priego-Parra, A. Triana-Romero, R. Bernal-Reyes, M.E. Icaza-Chávez, S.E. Martínez-Vázquez, M. Amieva-Balmori, A.D. Cano-Contreras, H. Vivanco-Cid, J.M. Remes-Troche   +8 more
doaj   +1 more source

Dynamics of Capillaria-hepatica-induced hepatic septal fibrosis in rats

Revista da Sociedade Brasileira de Medicina Tropical, 2010
INTRODUCTION: The pathogenesis of septal hepatic fibrosis, induced in rats by Capillaria hepatica infection, was studied with the aid of a large collection of stored paraffin blocks, representative of the different evolutive phases of fibrosis which ...
Lidiane Gaban, Cleber Douglas Lucinio Ramos, Aryon Almeida Barbosa Júnior, Márcia Maria de Souza, Zilton de Araújo Andrade   +4 more
doaj   +1 more source

HLA‐A*11:01 Identifies Patients at Risk for Persistent Viraemia and Advanced Fibrosis in HDV Infection

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 10, Page 1432-1447, November 2026.
The HLA‐A*11:01 allele is associated with persistent viraemia and advanced liver fibrosis in HDV infection. HLA‐A*11:01 carriers exhibit a reduced T‐cell repertoire, suggesting a narrower T‐cell response to the infection. ABSTRACT Background Hepatitis delta virus (HDV) infection causes the most severe form of viral hepatitis, with highly heterogeneous ...
Maria Francesca Cortese, Adriana Palom, Ariadna Rando Segura, Francesc Rudilla, Emma Enrich Rande, Arnau Puig Lopez, David Tabernero Caellas, Judit Vico Romero, Juan Carlos Ruiz‐Cobo, Mar Riveiro‐Barciela, Maria José Herrero, Maria Buti   +11 more
wiley   +1 more source

Immunological basis of septal fibrosis of the liver in Capillaria hepatica-infected rats

Brazilian Journal of Medical and Biological Research, 2003
Rats infected with the helminth Capillaria hepatica regularly develop septal fibrosis of the liver similar to that induced by repeated ip injections of pig serum.
Lemos Q.T., Magalhães-Santos I.F., Andrade Z.A.   +2 more
doaj  

Impact of YAQ001 on the Gut Microbiome, Permeability and Markers of Systemic Inflammation in Patients With Cirrhosis

Liver International, Volume 46, Issue 11, November 2026.
ABSTRACT Background & Aims YAQ001 is a novel, non‐absorbable, gut‐restricted, multiporous, carbon bead adsorbent. Pre‐clinical studies and a clinical trial suggested its therapeutic potential and safety in patients with cirrhosis. This substudy aimed to explore the effects of YAQ001 on the gut microbiome and their exploratory association with ...
Jinxia Liu, Fernando Garcia‐Guevara, Jane Macnaughtan, Yi Jin, Ainhoa Ferret‐Miñana, Frederick Clasen, Nicholas Yuen, Ramón Garcia Maset, Javier Ramón‐Azcón, Annarein J. C. Kerbert, Theo Portlock, Javier Martinez, Abeba Habtesion, Alexandra Phillips, Francesco De Chiara, Ganesh Ingavle, Tom Baldwin, Cesar Jimenez, Giacomo Zaccherini, Katherine Husi, Miguel Rodriguez‐Gandia, Paul Cordero‐Sanchez, Junpei Soeda, Jude A. Oben, Karen Church, Jia V. Li, Aarti Jalan, Adria Juanola, Elsa Sola, Simon Eaton, Carrie Morgan, Thomas Avery, Michal Kowalski, Daniel Green, Amir Gander, Lindsey Ann Edwards, I. Jane Cox, Helena Cortez‐Pinto, Reiner Wiest, Francois Durand, Paolo Caraceni, Roberto Elosua, Joan Vila, Marco Pavesi, Vicente Arroyo, Nathan Davies, Rajeshwar P. Mookerjee, Susan Sandeman, Gautam Mehta, Julian R. Marchesi, Agustin Albillos, Jennifer L. Rohn, Fausto Andreola, Saeed Shoaie, Rajiv Jalan   +54 more
wiley   +1 more source

Production of septal fibrosis of the liver by means of foreign protein injections into rats

Revista da Sociedade Brasileira de Medicina Tropical, 2003
Similarities and differences in antigenic humoral responses and electrophoretic patterns between Capillaria hepatica and pig-serum were investigated as a contribution to the understanding of hepatic fibrosis induced by the parenteral administration of ...
Bruna Magalhães Gotardo, Rodrigo Guimarães Andrade, Ludmila Fernandes Oliveira, Zilton A. Andrade   +3 more
doaj  

Endohepatology in the Management of Portal Hypertension in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Liver International, Volume 46, Issue 11, November 2026.
ABSTRACT Portal hypertension is the principal driver of decompensation in advanced chronic liver disease, yet in metabolic dysfunction‐associated steatotic liver disease (MASLD) it deviates from the classical sinusoidal paradigm. Growing evidence points to a mixed sinusoidal–presinusoidal phenotype in which the hepatic venous pressure gradient (HVPG ...
Michael Praktiknjo, Reiner Wiest, Andres Cardenas, Jonel Trebicka, Wim Laleman   +4 more
wiley   +1 more source

Frecuencia de fibrosis hepática avanzada en pacientes diabéticos con esteatosis hepática no alcohólica utilizando métodos no invasivos en un hospital general del tercer nivel en Lima - Perú [PDF]

, 2020
Introducción: La fibrosis hepática afecta el pronóstico de los pacientes con esteatosis hepática no alcohólica. La diabetes mellitus tipo 2 es un factor de riesgo para fibrosis hepática avanzada en pacientes con esteatosis hepática no alcohólica ...
Malca Hernández, Joselito, Cotacallapa Huayta, Nelsy Nilda   +1 more
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