Results 191 to 200 of about 21,222 (268)

Intermediate Filament Protein BFSP2 Controls Spindle Formation via HSC70‐Mediated Stabilization of CLTC During Oocyte meiosis

open access: yesAdvanced Science, EarlyView.
Meiosis is a specialized form of cell division that has different regulation and mechanisms with mitosis in numerous aspects. Particularly, meiosis I is unique and occurs only in germ cells to separate homologous chromosomes. Thus, determining how this unusual chromosome segregation behavior is established is central to understanding germ cell ...
Yu Li, Zihao Zhang, Yu Zhang, Bo Xiong
wiley   +1 more source

NamiRNA‐Enhancer Network: The Changing Era Challenge and Chance of miRNA

open access: yesAdvanced Science, EarlyView.
MiRNAs (miRNAs) regulate diverse biological processes across species. Unlike canonical miRNA‐mediated gene repression, Nuclear Activating miRNAs (NamiRNAs) can efficiently upregulate gene expression by targeting enhancers. This review systematically summarizes recent advances in NamiRNA research, elucidates the theory of NamiRNA‐Enhancer‐mediated Gene ...
Lu Chen   +13 more
wiley   +1 more source

Nature‐Inspired Nanostructures from Multiple‐Species Biomembranes: Rational Engineering and Therapeutic Applications in Tumor‐Targeted Nanomedicine

open access: yesAdvanced Science, EarlyView.
Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei   +10 more
wiley   +1 more source

Biodegradable Medical Implants: Reshaping Future Medical Practice

open access: yesAdvanced Science, EarlyView.
Biodegradable medical implants are transforming future healthcare by providing sustainable, biocompatible solutions that eliminate secondary removal procedures, enhancing patients’ physical and psychological comfort, and reducing economic burdens.
Bo Xia   +4 more
wiley   +1 more source

Unveiling Charge Transfer and Recombination Dynamics in 3D/2D Heterostructure via Ultrafast Spectroscopy for Efficient Perovskite Solar Cells

open access: yesAdvanced Science, EarlyView.
Charge transfer and recombination dynamics at 3D/2D perovskite heterostructure have been fully investigated via combined state‐of‐the‐art ultrafast spectroscopies, aiding to design of the desired 3D/2D perovskite heterostructure and thus push 3D/2D perovskite solar cell technology forward.
Di Li   +10 more
wiley   +1 more source

Smart Gated Hollow Mesoporous Silica Hydrogel for Targeting Endoplasmic Reticulum Stress and Promoting Periodontal Tissue Regeneration

open access: yesAdvanced Science, EarlyView.
The hollow mesoporous silica loaded with quercetin (HM‐QU@PEG) is combined with a thermosensitive anti‐bacterial matrix (TF127) to prepare HQUP@TF127. HQUP@TF127 effectively eliminates excessive ROS, alleviates endoplasmic reticulum stress, relieves mitochondrial calcium overload, and blocks the p53‐dependent apoptotic cascade. Furthermore, it enhances
Guichun Wang   +14 more
wiley   +1 more source

Biocompatible Mesoporous Materials for Bone Therapy

open access: yesAdvanced Science, EarlyView.
Biocompatible mesoporous materials (BMMs), characterized by high specific surface area, tunable pore size, different shapes and structures, and multidimensional functionalized modifications, have revolutionary applications in treating bone‐related diseases.
Biao Yu   +6 more
wiley   +1 more source

Polarization‐Sensitive Holotomography for Multidimensional Label‐Free Imaging and Characterization of Lipid Droplets in Cancer Cells

open access: yesAdvanced Science, EarlyView.
Polarization‐sensitive holotomography (PS‐HT) enables label‐free 3D imaging and quantitative analysis of lipid droplets by exploiting their intrinsic birefringence. Applied to prostate cell models, PS‐HT reveals glucose‐induced lipid accumulation in cancer cells and achieves near‐perfect classification of healthy and cancerous states.
Hossein Khadem   +4 more
wiley   +1 more source

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