Results 241 to 250 of about 570,529 (319)

MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang   +9 more
wiley   +1 more source

Suspended Tissue Open Microfluidic Patterning (STOMP)

open access: yesAdvanced Science, EarlyView.
Suspended Tissue Open Microfluidic Patterning (STOMP) is a method that enables precise spatial patterning within a single suspended tissue. By leveraging capillary pinning and open microfluidics, STOMP facilitates the creation of complex tissue interfaces such as diseased‐healthy boundaries and tissue‐tissue junctions. This method integrates mechanical
Amanda J. Haack   +22 more
wiley   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang   +4 more
wiley   +1 more source

Colorectal Cancer Cells–Derived Exosomal PIK3CA Mutation DNA Promotes Tumor Metastasis by Activating Fibroblast and Affecting Tumor Metastatic Microenvironment

open access: yesAdvanced Science, EarlyView.
PIK3CAH1047R DNA in colorectal cancer (CRC) cell‐derived exosomes can be delivered into recipient fibroblasts, where it is transcribed and translated, leading to the activation of fibroblasts into cancer‐associated fibroblasts, which secrete elevated levels of IL6. The simultaneous detection and targeting of PIK3CAH1047R mutation and IL6 may serve as a
Rui Wang   +6 more
wiley   +1 more source

Tailored Fluorescent Metal–Organic Frameworks Hybrid Membrane Sensor Arrays: Simultaneous and Selective Quantification of Multiple Antibiotics

open access: yesAdvanced Science, EarlyView.
A filterable paper‐based fluorescent metal–organic frameworks (MOFs) sensor array is developed for one‐to‐one recognition and simultaneous quantification of multiple antibiotics. Three representative MOFs are strategically designed to exhibit exceptional affinity and specificity for the target antibiotic.
Tongtong Ma   +7 more
wiley   +1 more source

Ultralow Overpotential in Rechargeable Li–CO2 Batteries Enabled by Caesium Phosphomolybdate as an Effective Redox Catalyst

open access: yesAdvanced Science, EarlyView.
This study represents the first application of a Keggin‐type polyoxometalate, caesium phosphomolybdate (CPM), as a bifunctional redox catalyst for rechargeable Li–CO2 batteries. CPM significantly reduced the potential gap between discharge and charge reactions to 0.67 V, outperforming most reported catalysts. It also exhibited a high discharge capacity
Mahsa Masoudi   +9 more
wiley   +1 more source

Histology of control sample: fibrous cap atheroma.

open access: yes, 2015
C. Janna   +7 more
semanticscholar   +1 more source

Nano/Micro Metal‐Organic Framework‐Derived Porous Carbon with Rich Nitrogen Sites as Efficient Iodine Hosts for Aqueous Zinc‐Iodine Batteries

open access: yesAdvanced Science, EarlyView.
A cubic zinc‐based metal‐organic framework derived (Zn‐MOF‐derived) porous nitrogen‐doped carbon host is engineered to immobilize iodine, leveraging its hierarchical porosity and rich nitrogen sites to suppress polyiodide shuttling and enhance redox kinetics in zinc–iodine (Zn–I2) batteries.
Yong Li   +8 more
wiley   +1 more source

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