Results 241 to 250 of about 570,529 (319)
MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang+9 more
wiley +1 more source
Suspended Tissue Open Microfluidic Patterning (STOMP)
Suspended Tissue Open Microfluidic Patterning (STOMP) is a method that enables precise spatial patterning within a single suspended tissue. By leveraging capillary pinning and open microfluidics, STOMP facilitates the creation of complex tissue interfaces such as diseased‐healthy boundaries and tissue‐tissue junctions. This method integrates mechanical
Amanda J. Haack+22 more
wiley +1 more source
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang+4 more
wiley +1 more source
PIK3CAH1047R DNA in colorectal cancer (CRC) cell‐derived exosomes can be delivered into recipient fibroblasts, where it is transcribed and translated, leading to the activation of fibroblasts into cancer‐associated fibroblasts, which secrete elevated levels of IL6. The simultaneous detection and targeting of PIK3CAH1047R mutation and IL6 may serve as a
Rui Wang+6 more
wiley +1 more source
A filterable paper‐based fluorescent metal–organic frameworks (MOFs) sensor array is developed for one‐to‐one recognition and simultaneous quantification of multiple antibiotics. Three representative MOFs are strategically designed to exhibit exceptional affinity and specificity for the target antibiotic.
Tongtong Ma+7 more
wiley +1 more source
Correction to: Mitochondrial Respiration Is Reduced in Atherosclerosis, Promoting Necrotic Core Formation and Reducing Relative Fibrous Cap Thickness. [PDF]
europepmc +1 more source
This study represents the first application of a Keggin‐type polyoxometalate, caesium phosphomolybdate (CPM), as a bifunctional redox catalyst for rechargeable Li–CO2 batteries. CPM significantly reduced the potential gap between discharge and charge reactions to 0.67 V, outperforming most reported catalysts. It also exhibited a high discharge capacity
Mahsa Masoudi+9 more
wiley +1 more source
Histology of control sample: fibrous cap atheroma.
C. Janna+7 more
semanticscholar +1 more source
A cubic zinc‐based metal‐organic framework derived (Zn‐MOF‐derived) porous nitrogen‐doped carbon host is engineered to immobilize iodine, leveraging its hierarchical porosity and rich nitrogen sites to suppress polyiodide shuttling and enhance redox kinetics in zinc–iodine (Zn–I2) batteries.
Yong Li+8 more
wiley +1 more source