Results 21 to 30 of about 21,222 (268)

Coronary plaque composition influences biomechanical stress and predicts plaque rupture in a morpho-mechanic OCT analysis

eLife, 2021
Plaque rupture occurs if stress within coronary lesions exceeds the protection exerted by the fibrous cap overlying the necrotic lipid core. However, very little is known about the biomechanical stress exerting this disrupting force.
Andrea Milzi, Enrico Domenico Lemma, Rosalia Dettori, Kathrin Burgmaier, Nikolaus Marx, Sebastian Reith, Mathias Burgmaier   +6 more
doaj   +1 more source

Gender-based in vivo comparison of culprit plaque characteristics and plaque microstructures using optical coherence tomography in acute coronary syndrome [PDF]

Journal of Cardiovascular and Thoracic Research, 2021
Introduction: Women perform worse after acute coronary syndrome (ACS) than men. The reason for these differences is unclear. The aim was to ascertain gender differences in the culprit plaque characteristics in ACS.
Krishna Prasad, Sreeniavs Reddy S, Jaspreet Kaur, Raghavendra Rao k, Suraj Kumar, Vikas Kadiyala, Jeet Ram Kashyap, Garima Panwar   +7 more
doaj   +1 more source

Changes in blood vessel maturation in the fibrous cap of the tumor rim [PDF]

Cancer Science, 2011
It is widely accepted that blood vessels in the tumor microenvironment are immature because mural cell (MC) adhesion to endothelial cells (ECs) is broadly lacking. Hyperpermeability of the tumor vasculature then results in interstitial hypertension that mitigates against penetration of anticancer drugs into the depths of the tumor.
Hisamichi Naito, Kazuhiro Takara, Taku Wakabayashi, Hiroki Kawahara, Hiroyasu Kidoya, Nobuyuki Takakura   +5 more
openalex   +4 more sources

Optical Coherence Tomography and Fibrous Cap Characterization [PDF]

Current Cardiovascular Imaging Reports, 2011
The pathophysiology of acute coronary syndromes has long been associated with atherosclerotic plaque rupture. Inflammation, thinning, and disruption of the fibrous cap have been implicated with the final processes leading to plaque rupture, but confirmation of these mechanisms of coronary thrombosis in humans has been hampered by the lack of imaging ...
Daniel Chamié, Zhao Wang, Andrew M. Rollins, Marco A. Costa, Hiram G. Bezerra   +4 more
openaire   +3 more sources

Fibrous Cap Thickness and Stability of Carotid Atheromata [PDF]

Stroke, 2006
To the Editor: We read with great interest the article by Li et al.1 The authors are to be congratulated for their excellent study. We totally agree that clinical decision-making in patients with carotid disease should take into consideration plaque morphology (eg, fibrous cap thickness) as well as the degree of lumen stenosis.
Theodoros Karapanayiotides, Gérald Devuyst   +1 more
openaire   +3 more sources

The Effect of Carotid Plaque Morphology on Longitudinal Fibrous Cap Stress Levels

World Journal of Mechanics, 2012
Background and Purpose: Rupture of vulnerable carotid atherosclerotic plaques is a major cause of stroke. Stress levels may reflect risk of rupture in patients with carotid atherosclerotic plaques. Features thought to influence the risk of plaque rupture include the degree of stenosis, lipid-rich necrotic core (LR-NC) size, and thickness of the ...
Samuel A. Thrysøe, Anders F. Stegmann, Nikolaj Eldrup, Anette Klærke, William P. Paaske, Won Yong Kim, Jens Vinge Nygaard   +6 more
openalex   +4 more sources

Magnetic Resonance Imaging Identifies the Fibrous Cap in Atherosclerotic Abdominal Aortic Aneurysm [PDF]

Circulation, 2004
Background— MRI can distinguish components of atherosclerotic plaque. We hypothesized that contrast enhancement with gadolinium-DTPA (Gd-DTPA) could aid in the differentiation of plaque components in abdominal aortic aneurysm (AAA). Methods and Results—
Christopher M. Kramer, Lisa A. Cerilli, Klaus D. Hagspiel, Joseph M DiMaria, Frederick H. Epstein, John A. Kern   +5 more
openalex   +4 more sources

No fibrous cap and pannus formation in an On-X mechanical aortic valve [PDF]

Interactive CardioVascular and Thoracic Surgery, 2020
Abstract Mechanical cardiac valves placed in the aortic position can show different amounts of pannus under the aortic ring. A 68-year-old patient had undergone mitral annuloplasty with a 30-mm rigid ring and aortic valve replacement with a 21-mm On-X mechanical valve for mitral regurgitation and aortic valve stenosis 10 years and 3 ...
Dae Woong Ryu, Jong Bum Choi
openaire   +3 more sources

A two-phase model of early fibrous cap formation in atherosclerosis [PDF]

Journal of Theoretical Biology, 2018
Atherosclerotic plaque growth is characterised by chronic inflammation that promotes accumulation of cellular debris and extracellular fat in the inner artery wall. This material is highly thrombogenic, and plaque rupture can lead to the formation of blood clots that occlude major arteries and cause myocardial infarction or stroke. In advanced plaques,
Michael G. Watson, Helen M. Byrne, Charlie Macaskill, Mary R. Myerscough   +3 more
openaire   +4 more sources

Consideration of stiffness of wall layers is decisive for patient-specific analysis of carotid artery with atheroma.

PLoS ONE, 2020
The paper deals with the impact of chosen geometric and material factors on maximal stresses in carotid atherosclerotic plaque calculated using patient-specific finite element models.
Ondřej Lisický, Aneta Malá, Zdeněk Bednařík, Tomáš Novotný, Jiří Burša   +4 more
doaj   +2 more sources