Results 31 to 40 of about 21,222 (268)

Dapatkah Matrix Metalloproteinase Memprediksi Luasnya Kerusakan Miokard?

Majalah Kardiologi Indonesia, 2013
Trombosis arteri merupakan dasar terjadinya sindrom koroner akut. Sebagian besar trombosis terjadi pada robekan plak pada bagian fibrous cap yang tipis.
Yoga Yuniadi
doaj   +1 more source

Using optical coherence tomography and intravascular ultrasound imaging to quantify coronary plaque cap thickness and vulnerability: a pilot study

BioMedical Engineering OnLine, 2020
Background Detecting coronary vulnerable plaques in vivo and assessing their vulnerability have been great challenges for clinicians and the research community.
Rui Lv, Akiko Maehara, Mitsuaki Matsumura, Liang Wang, Qingyu Wang, Caining Zhang, Xiaoya Guo, Habib Samady, Don P. Giddens, Jie Zheng, Gary S. Mintz, Dalin Tang   +11 more
doaj   +1 more source

TCT-355 An Automated Computational Method for Quantification of Total Fibrous Cap Volume and Mean Fibrous Cap Thickness with Optical Coherence Tomography

Journal of the American College of Cardiology, 2015
A thin fibrous cap (FC) is associated with plaque rupture and adverse events. Accurate measurements of FC thickness by optical coherence tomography (OCT) is possible but only with manual, point-by-point analyses which is dependent on human visual assessment of the fibrous cap border, subject ...
Vincent Woo, Zhi Chen, Taishi Hirai, Joseph R. Weber, Tomáš Kovárník, Andreas Wahle, Milan Sonka, John J. López   +7 more
openalex   +3 more sources

Extensive Lipid Lowering, Thickness of the Fibrous Caps, and the Plaque Stability

European Heart Journal Open
Shinya Goto, Shinichi Goto
openalex   +3 more sources

Clinical Imaging of ACS With Ruptured or Intact Fibrous Caps

JACC: Cardiovascular Imaging, 2015
In vivo intravascular imaging of culprit plaques in acute coronary syndrome (ACS) may shed light on the plaque substrate of acute thrombosis, either a ruptured fibrous cap (RFC) or an intact fibrous cap (IFC).
Nupoor Narula, Takahide Kodama, Eloisa Arbustini   +2 more
openaire   +3 more sources

The fibrous cap: a promising target in the pharmacotherapy of atherosclerosis

Biomedical Reviews, 2019
Recent advances have shed light on the relationship between smooth muscle cell (SMC) phenotypic modulation, resolution of inflammation and atherosclerotic plaque stability. The thick fibrous cap covering the lipid core of plaques is composed of bundles of SMC and collagen fibers and few macrophages and lymphocytes, all of which make the plaque ...
Maria Zhelyazkova-Savova, Stanislav Yanev, George N. Chaldakov   +2 more
openaire   +2 more sources

Role Of Metalloproteinases in Plaque Rupture

International Journal of Gerontology, 2007
Rupture of the fibrous cap over an atherosclerotic plaque is the main cause of myocardial infarctions and strokes. Plaques vulnerable to rupture have a relatively thin fibrous cap, are highly inflamed and contain less structural collagen.
Andrew C Newby
doaj   +1 more source

Platelet hyaluronidase 2 enrichment in acute coronary syndromes: a conceivable role in monocyte-platelet aggregate formation

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Acute Coronary Syndromes (ACS) with plaque erosion display dysregulated hyaluronan metabolism, with increased hyaluronidase-2 (HYAL2) expression. However, the expression and the role of this enzyme on platelets has never been explored.
Ramona Vinci, Daniela Pedicino, Alessia D’Aiello, Pellegrino Ciampi, Myriana Ponzo, Alice Bonanni, Giulio Russo, Rocco Antonio Montone, Massimo Massetti, Filippo Crea, Giovanna Liuzzo   +10 more
doaj   +1 more source

Fibrous Cap Thickness by Optical Coherence Tomography In Vivo

Journal of the American College of Cardiology, 2017
Optical coherence tomography (OCT) imaging is considered to be the only imaging modality with sufficient resolution to measure fibrous cap thickness (FCT) in vivo. However, reproducibility of the measurements in vivo has been unsatisfactory.The authors aimed to investigate whether satisfactory reproducibility of FCT measurements by OCT in vivo can be ...
Samin K. Sharma, Roxana Mehran, Usman Baber, Yuliya Vengrenyuk, Akiko Maehara, Annapoorna Kini, Pedro R. Moreno, Jacobo Pena, Mitsuaki Matsumura, Jagat Narula, Takahiro Yoshimura   +10 more
openaire   +3 more sources

Fibrotic Signaling in Cardiac Fibroblasts and Vascular Smooth Muscle Cells: The Dual Roles of Fibrosis in HFpEF and CAD

Cells, 2022
Patients with heart failure with preserved ejection fraction (HFpEF) and atherosclerosis-driven coronary artery disease (CAD) will have ongoing fibrotic remodeling both in the myocardium and in atherosclerotic plaques.
Julian C. Bachmann, Simon J. Baumgart, Anna K. Uryga, Markus H. Bosteen, Giulia Borghetti, Michael Nyberg, Kate M. Herum   +6 more
doaj   +1 more source