Results 41 to 50 of about 21,222 (268)
Ultrasound Measurement of the Fibrous Cap in Symptomatic and Asymptomatic Atheromatous Carotid Plaques [PDF]
Circulation, 2005 Background— Fibrous cap thickness (FCT) is an important determinant of atheroma stability. We evaluated the feasibility and potential clinical implications of measuring the FCT of internal carotid artery plaques with a new ultrasound system based on boundary detection by dynamic programming.
Devuyst, Gérald +10 more
openaire +4 more sources
Journal of Biomechanical Science and Engineering, 2016 Atherosclerosis is a major cause of mortality and morbidity worldwide. In advanced atheromatous plaques, stiffening is often accompanied by calcification.
Hamed ESMAEILI MONIR +4 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2021 Objective: This study aimed to investigate the effect of smoking on morphological changes in non-culprit plaques in acute coronary syndrome (ACS) patients at 1 year after percutaneous coronary intervention (PCI), using optical coherence tomography (OCT ...
Xiling Zhang +9 more
doaj +1 more source
MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions [PDF]
Circulation Research, 2017 Rationale: In the search for markers and modulators of vascular disease, microRNAs (miRNAs) have emerged as potent therapeutic targets. Objective: To investigate miRNAs of clinical interest in patients with unstable carotid ...
Eken, Suzanne M. +23 more
openaire +3 more sources
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017 BackgroundPrevious studies have demonstrated that statin therapy improves cardiac outcomes, probably by stabilizing thin‐cap fibroatheroma in patients with coronary artery disease.
Yoshiyasu Minami +9 more
doaj +1 more source
Fibrous Caps in Atherosclerosis Form by Notch-Dependent Mechanisms Common to Arterial Media Development [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2020 Objective: Atheromatous fibrous caps are produced by smooth muscle cells (SMCs) that are recruited to the subendothelial space. We tested whether the recruitment mechanisms are the same as in embryonic artery development, which relies prominently on Notch signaling to form the subendothelial medial SMC layers.
Donal MacGrogan +10 more
openaire +6 more sources
Revised microcalcification hypothesis for fibrous cap rupture in human coronary arteries [PDF]
Proceedings of the National Academy of Sciences, 2013 Using 2.1-µm high-resolution microcomputed tomography, we have examined the spatial distribution, clustering, and shape of nearly 35,000 microcalcifications (µCalcs) ≥ 5 µm in the fibrous caps of 22 nonruptured human atherosclerotic plaques.
Adreanne Kelly-Arnold +5 more
openaire +2 more sources
How Does Calcification Influence Plaque Vulnerability? Insights from Fatigue Analysis
The Scientific World Journal, 2014 Background. Calcification is commonly believed to be associated with cardiovascular disease burden. But whether or not the calcifications have a negative effect on plaque vulnerability is still under debate. Methods and Results.
Baijian Wu, Xuan Pei, Zhi-Yong Li
doaj +1 more source
BMC Cardiovascular Disorders, 2021 Background Activating transcription factor 3 (ATF3) is an early response gene that is activated in response to atherosclerotic stimulation and may be an important factor in inhibiting the progression of atherosclerosis.
J. Peng +9 more
doaj +1 more source
Gut Microbiota and Coronary Plaque Characteristics
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background The relationship between gut microbiota and in vivo coronary plaque characteristics has not been reported. This study was conducted to investigate the relationship between gut microbiota and coronary plaque characteristics in patients with ...
Akihiro Nakajima +25 more
doaj +1 more source