Results 51 to 60 of about 539,731 (302)

Consideration of stiffness of wall layers is decisive for patient-specific analysis of carotid artery with atheroma.

PLoS ONE, 2020
The paper deals with the impact of chosen geometric and material factors on maximal stresses in carotid atherosclerotic plaque calculated using patient-specific finite element models.
Ondřej Lisický, Aneta Malá, Zdeněk Bednařík, Tomáš Novotný, Jiří Burša   +4 more
doaj   +2 more sources

Dapatkah Matrix Metalloproteinase Memprediksi Luasnya Kerusakan Miokard?

Majalah Kardiologi Indonesia, 2013
Trombosis arteri merupakan dasar terjadinya sindrom koroner akut. Sebagian besar trombosis terjadi pada robekan plak pada bagian fibrous cap yang tipis.
Yoga Yuniadi
doaj   +1 more source

Using optical coherence tomography and intravascular ultrasound imaging to quantify coronary plaque cap thickness and vulnerability: a pilot study

BioMedical Engineering OnLine, 2020
Background Detecting coronary vulnerable plaques in vivo and assessing their vulnerability have been great challenges for clinicians and the research community.
Rui Lv, Akiko Maehara, Mitsuaki Matsumura, Liang Wang, Qingyu Wang, Caining Zhang, Xiaoya Guo, Habib Samady, Don P. Giddens, Jie Zheng, Gary S. Mintz, Dalin Tang   +11 more
doaj   +1 more source

Clinical Imaging of ACS With Ruptured or Intact Fibrous Caps

JACC: Cardiovascular Imaging, 2015
In vivo intravascular imaging of culprit plaques in acute coronary syndrome (ACS) may shed light on the plaque substrate of acute thrombosis, either a ruptured fibrous cap (RFC) or an intact fibrous cap (IFC).
Nupoor Narula, Takahide Kodama, Eloisa Arbustini   +2 more
openaire   +3 more sources

Ultrasound Measurement of the Fibrous Cap in Symptomatic and Asymptomatic Atheromatous Carotid Plaques [PDF]

Circulation, 2005
Background— Fibrous cap thickness (FCT) is an important determinant of atheroma stability. We evaluated the feasibility and potential clinical implications of measuring the FCT of internal carotid artery plaques with a new ultrasound system based on boundary detection by dynamic programming.
Devuyst, G., Karapanayiotides, T., Pusztaszeri, M., Lobrinus, J., Jonasson, L., Cuisenaire, O., Kalangos, A., Despland, P., Thiran, J., Ruchat, P., Bogousslavsky, J.   +10 more
openaire   +4 more sources

Role Of Metalloproteinases in Plaque Rupture

International Journal of Gerontology, 2007
Rupture of the fibrous cap over an atherosclerotic plaque is the main cause of myocardial infarctions and strokes. Plaques vulnerable to rupture have a relatively thin fibrous cap, are highly inflamed and contain less structural collagen.
Andrew C Newby
doaj   +1 more source

Platelet hyaluronidase 2 enrichment in acute coronary syndromes: a conceivable role in monocyte-platelet aggregate formation

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Acute Coronary Syndromes (ACS) with plaque erosion display dysregulated hyaluronan metabolism, with increased hyaluronidase-2 (HYAL2) expression. However, the expression and the role of this enzyme on platelets has never been explored.
Ramona Vinci, Daniela Pedicino, Alessia D’Aiello, Pellegrino Ciampi, Myriana Ponzo, Alice Bonanni, Giulio Russo, Rocco Antonio Montone, Massimo Massetti, Filippo Crea, Giovanna Liuzzo   +10 more
doaj   +1 more source

In-silico modeling of the micromechanics of fibrous scaffolds and stiffness sensing by cells [PDF]

, 2021
Mechanical properties of the tissue engineering scaffolds are known to play a crucial role in tissue regeneration. Here, we have utilized discrete network and finite element models to study fibrous scaffold mechanics and its dependence on structure.
arxiv   +1 more source

Assessment of the relationship between deformation characteristics and the presence of calcification in human atheromatous plaques using uniaxial stretching evaluations with digital image correlation, CT scanning and histological examination

Journal of Biomechanical Science and Engineering, 2016
Atherosclerosis is a major cause of mortality and morbidity worldwide. In advanced atheromatous plaques, stiffening is often accompanied by calcification.
Hamed ESMAEILI MONIR, Hiroshi YAMADA, Noriyuki SAKATA, Yasuyuki MORITA, Yutaka NAKASHIMA   +4 more
doaj   +1 more source

Fibrotic Signaling in Cardiac Fibroblasts and Vascular Smooth Muscle Cells: The Dual Roles of Fibrosis in HFpEF and CAD

Cells, 2022
Patients with heart failure with preserved ejection fraction (HFpEF) and atherosclerosis-driven coronary artery disease (CAD) will have ongoing fibrotic remodeling both in the myocardium and in atherosclerotic plaques.
Julian C. Bachmann, Simon J. Baumgart, Anna K. Uryga, Markus H. Bosteen, Giulia Borghetti, Michael Nyberg, Kate M. Herum   +6 more
doaj   +1 more source