Results 51 to 60 of about 593,549 (321)

A clinically relevant model of osteoinduction: a process requiring calcium phosphate and BMP/Wnt signalling [PDF]

, 2010
In this study, we investigated a clinically relevant model of in vivo ectopic bone formation utilizing human periosteum derived cells (HPDCs) seeded in a Collagraft carrier and explored the mechanisms by which this process is driven.
Eyckmans, Jeroen, Luyten, F. P., Roberts, S. J., Schrooten, J.   +3 more
core   +1 more source

Utility of mass spectrometry for the diagnosis of the unstable coronary plaque. [PDF]

, 2015
Mass spectrometry is a powerful technique that is used to identify unknown compounds, to quantify known materials, and to elucidate the structure and chemical properties of molecules.
Hassan, M, Jacob, SS, Yacoub, MH
core   +1 more source

Clinical Imaging of ACS With Ruptured or Intact Fibrous Caps

JACC: Cardiovascular Imaging, 2015
In vivo intravascular imaging of culprit plaques in acute coronary syndrome (ACS) may shed light on the plaque substrate of acute thrombosis, either a ruptured fibrous cap (RFC) or an intact fibrous cap (IFC).
Arbustini, Eloisa, Narula, Nupoor, Kodama, Takahide   +2 more
openaire   +2 more sources

Role Of Metalloproteinases in Plaque Rupture

International Journal of Gerontology, 2007
Rupture of the fibrous cap over an atherosclerotic plaque is the main cause of myocardial infarctions and strokes. Plaques vulnerable to rupture have a relatively thin fibrous cap, are highly inflamed and contain less structural collagen.
Andrew C Newby
doaj   +1 more source

Orthopedic surgery increases atherosclerotic lesions and necrotic core area in ApoE-/- mice [PDF]

, 2016
Background and aims Observational studies show a peak incidence of cardiovascular events after major surgery. For example, the risk of myocardial infarction increases 25-fold early after hip replacement.
Chen, Cohen, Corrales-Medina, Dutta, Dutta, Gualandro, Hans W.M. Niessen, Hanson, Ilse P.A. Zethof, Janssen, Kaynar, King, Kleemann, Lalmohamed, Landesberg, Lars F.H. Theyse, Libby, Martine C. Morrison, Moore, Morrison, Naghavi, Paul A.J. Krijnen, Reid, Rianne van der Linden, Robert Kleemann, Santos-Gallego, Santos-Gallego, Santos-Gallego, Seimon, Smeeth, Tan, Thompson, Thompson, Van der Donckt, van Dijk, Virmani, Virmani, Wessel W. Fuijkschot, Yvo M. Smulders, Zhang   +39 more
core   +2 more sources

Platelet hyaluronidase 2 enrichment in acute coronary syndromes: a conceivable role in monocyte-platelet aggregate formation

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Acute Coronary Syndromes (ACS) with plaque erosion display dysregulated hyaluronan metabolism, with increased hyaluronidase-2 (HYAL2) expression. However, the expression and the role of this enzyme on platelets has never been explored.
Ramona Vinci, Daniela Pedicino, Alessia D’Aiello, Pellegrino Ciampi, Myriana Ponzo, Alice Bonanni, Giulio Russo, Rocco Antonio Montone, Massimo Massetti, Filippo Crea, Giovanna Liuzzo   +10 more
doaj   +1 more source

Fibrotic Signaling in Cardiac Fibroblasts and Vascular Smooth Muscle Cells: The Dual Roles of Fibrosis in HFpEF and CAD

Cells, 2022
Patients with heart failure with preserved ejection fraction (HFpEF) and atherosclerosis-driven coronary artery disease (CAD) will have ongoing fibrotic remodeling both in the myocardium and in atherosclerotic plaques.
Julian C. Bachmann, Simon J. Baumgart, Anna K. Uryga, Markus H. Bosteen, Giulia Borghetti, Michael Nyberg, Kate M. Herum   +6 more
doaj   +1 more source

Accuracy of magnetic resonance imaging to identify pseudocapsule invasion in renal tumors [PDF]

, 2020
Purpose: To evaluate accuracy of MRI in detecting renal tumor pseudocapsule (PC) invasion and to propose a classification based on imaging of PC status in patients with renal cell carcinoma.
Altobelli, Emanuela, Angeletti, Silvia, Bellangino, Mariangela, Catalano, Carlo, Ciccozzi, Massimo, Del Monte, Maurizio, D’ovidio, Giulia, Faiella Eliodoro, Gallucci, Michele, Grasso, Francesco Rosario, Mastroianni, Riccardo, Muto, Giovanni, Panebianco, Valeria, Papalia, Rocco, Scarpa, Roberto Mario, Simone, Giuseppe   +15 more
core   +1 more source

Volumetric quantification of fibrous caps using intravascular optical coherence tomography

Biomedical Optics Express, 2012
The rupture of thin-cap fibroatheroma accounts for most acute coronary events. Optical Coherence Tomography (OCT) allows quantification of fibrous cap (FC) thickness in vivo. Conventional manual analysis, by visually determining the thinnest part of the FC is subject to inter-observer variability and does not capture the 3-D morphology of the FC.
Wang, Zhao, Chamie, Daniel, Bezerra, Hiram G., Yamamoto, Hirosada, Kanovsky, Jan, Wilson, David L., Costa, Marco A., Rollins, Andrew M.   +7 more
openaire   +2 more sources

Assessment of the relationship between deformation characteristics and the presence of calcification in human atheromatous plaques using uniaxial stretching evaluations with digital image correlation, CT scanning and histological examination

Journal of Biomechanical Science and Engineering, 2016
Atherosclerosis is a major cause of mortality and morbidity worldwide. In advanced atheromatous plaques, stiffening is often accompanied by calcification.
Hamed ESMAEILI MONIR, Hiroshi YAMADA, Noriyuki SAKATA, Yasuyuki MORITA, Yutaka NAKASHIMA   +4 more
doaj   +1 more source