Results 71 to 80 of about 593,549 (321)

The role of p53 in atherosclerosis [PDF]

, 2006
Although the role of the tumour suppressor gene p53 is well known in cancer, recent studies have highlighted a fundamental role for p53 in regulating cells in the advanced atherosclerotic plaque, the major cause of heart attacks and stroke. In particular,
Bennett, M., Mercer, J.R.
core   +1 more source

TCT-355 An Automated Computational Method for Quantification of Total Fibrous Cap Volume and Mean Fibrous Cap Thickness with Optical Coherence Tomography

Journal of the American College of Cardiology, 2015
A thin fibrous cap (FC) is associated with plaque rupture and adverse events. Accurate measurements of FC thickness by optical coherence tomography (OCT) is possible but only with manual, point-by-point analyses which is dependent on human visual assessment of the fibrous cap border, subject ...
Woo, Vincent, Chen, Zhi, Hirai, Taishi, Weber, Joseph R., Kovarnik, Tomas, Wahle, Andreas, Sonka, Milan, Lopez, John J.   +7 more
openaire   +1 more source

The relationship between fibrous cap status or plaque surface morphology and intraplaque hemorrhage volume over time: The PARISK Study

Journal of Stroke and Cerebrovascular Diseases
Background: Carotid intraplaque hemorrhage (IPH) is a strong predictor of stroke, but factors contributing to IPH development are incompletely understood.
Mohamed Kassem, Tahnee Gorissen, Mohammad Albenwan, Juul Bierens, Dianne H.K. van Dam-Nolen, Madieke I. Liem, Paul A.M. Hofman, Joachim E Wildberger, Jeroen Hendrikse, Werner Mess, Paul J. Nederkoorn, Daniel Bos, Patty Nelemans, Robert J. van Oostenbrugge, M. Eline Kooi   +14 more
doaj   +1 more source

Mathematical models for vulnerable plaques [PDF]

, 2009
A plaque is an accumulation and swelling in the artery walls and typically consists of cells, cell debris, lipids, calcium deposits and fibrous connective tissue.
Bell, J., Breward, C., Chou, T., Fok, P.-W., Haugh, J. M., Li, Q., Rossi, L., Walter, A., Yang, X., Zemlyanova, A., Zhang, N.   +10 more
core  

Advances in procedural techniques--antegrade. [PDF]

, 2014
There have been many technological advances in antegrade CTO PCI, but perhaps most importantly has been the evolution of the "hybrid' approach where ideally there exists a seamless interplay of antegrade wiring, antegrade dissection re-entry and ...
Spratt, JC, Wilson, W
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Functional morphology of the primary olfactory centers in the brain of the hermit crab Coenobita clypeatus (Anomala, Coenobitidae)

, 2020
Terrestrial hermit crabs of the genus Coenobita display strong behavioral responses to volatile odors and are attracted by chemical cues of various potential food sources.
Dircksen, H., Hansson, B., Harzsch, S., Kirchhoff, T., Polanska, M.   +4 more
core   +1 more source

CT attenuation analysis of carotid intraplaque hemorrhage [PDF]

, 2018
Background and Purpose: Intraplaque hemorrhage is considered a leading parameter of carotid plaque vulnerability. Our purpose was to assess the CT characteristics of intraplaque hemorrhage with histopathologic correlation to identify features that allow ...
Bassareo, P. P., Cecco, C. N. D., Faa, X. G., Francone, M., Lai, L., Montisci, R., Saba, L., Sanfilippo, Rosa, Suri, J. S.   +8 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Comparison of Predictive Ability of Computed Tomography and Magnetic Resonance Imaging in Patients with Carotid Atherosclerosis Complicated with Stroke

Iranian Journal of Public Health, 2019
Background: To investigate the characterizations of CT (computed tomography) and MRI (magnetic resonance imaging) in patients with carotid atherosclerosis.
Jiangfeng ZHOU, Hongling CHEN, Tao YANG, Cuihong XING, Fengxia JIA   +4 more
doaj   +1 more source