Results 21 to 30 of about 17,584 (119)

Epilepsy characteristics in patients with muscle‐eye‐brain disease: A systematic review of electroclinical features

open access: yesEpileptic Disorders, EarlyView.
Abstract Background and Objectives Muscle‐Eye‐Brain disease (MEB) is a dystroglycanopathy that belongs to the congenital muscular dystrophies. Central nervous system manifestations include congenital brain abnormalities, neurodevelopmental delay, and epilepsy, making it a rare but important cause of developmental and epileptic encephalopathy.
Stefania Kalampokini   +6 more
wiley   +1 more source

Cognition in adults with bottom‐of‐sulcus dysplasia and the consequences of focal resection

open access: yesEpilepsia, EarlyView.
Abstract Objective To determine whether there are cognitive consequences of bottom‐of‐sulcus dysplasia (BOSD) when assessed as adults and whether focal resection of these lesions leads to change in cognition. Methods We studied 42 adults, of whom 39 underwent focal resection targeting the lesion.
Carmen J. Zheng   +4 more
wiley   +1 more source

Glymphatic dysfunction couples with cortical excitation–inhibition imbalance in epilepsy: Evidence from Rasmussen encephalitis

open access: yesEpilepsia, EarlyView.
Cong Fu et al. demonstrate that glymphatic system dysfunction is linked to enhanced inhibitory cortical activity using diffusion MRI and EEG. These findings highlight a mechanistic link between perivascular fluid dynamics and neuronal activity, suggesting a role for glymphatic function in maintaining cortical stability in epilepsy.
Cong Fu   +11 more
wiley   +1 more source

Immune, molecular and genetic profiles of gastric signet ring cell carcinoma: Recent progress and future challenges

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang   +5 more
wiley   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

open access: yesiNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu   +4 more
wiley   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza   +2 more
wiley   +1 more source

Adding lateral retinacular release to medial patellofemoral ligament reconstruction reconstruction has no effect on patellar height: A prospective randomised controlled trial

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate the effect of medial patellofemoral ligament (MPFL) reconstruction with or without lateral retinacular release (LRR) on patellar height in patients with recurrent patellar dislocation (RPD). It was hypothesised that the addition of LRR would not significantly modify patellar height compared with isolated MPFL reconstruction.
François Fauré   +4 more
wiley   +1 more source

Clinical and Histopathological Assessment of the Field of Cancerization in Human Skin Before and After Treatment With a 1927‐nm Thulium Fractional Laser

open access: yesLasers in Surgery and Medicine, EarlyView.
ABSTRACT Background Field cancerization is a major concern in photodamaged skin due to its risk of progression to squamous cell carcinoma. The 1927‐nm thulium laser has emerged as a promising therapy, but its isolated effects on this condition remain underexplored.
Livia Maria Oliveira Salviano   +6 more
wiley   +1 more source

The Spectrum of Abnormal Tongue Movements: Review of Phenomenology, Etiology, and Differential Diagnosis

open access: yesMovement Disorders Clinical Practice, EarlyView.
ABSTRACT Background Classifying abnormal tongue movements is challenging due to their varied presentations and limited visibility compared to other body parts. Accurate identification of the phenomenology guides physical examination and can point to specific diagnoses.
Nathaniel Bendahan   +4 more
wiley   +1 more source

Model Predictive Filtering MR Temperature Imaging for Laser‐Induced Interstitial Thermotherapy

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To evaluate the use of the Model Predictive Filtering (MPF) method to improve temporal resolution of magnetic resonance temperature imaging (MRTI) for monitoring laser interstitial thermal therapy (LITT) ablations. Methods Using a Green's function method for solving differential equations, a treatment‐specific power matrix Q was ...
Joshua Marchant   +3 more
wiley   +1 more source

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