Results 51 to 60 of about 281,511 (272)
Gynecologic and reproductive outcomes in fibrous dysplasia/McCune-Albright syndrome
Orphanet Journal of Rare Diseases, 2019 BackgroundAutonomous ovarian activation with recurrent estrogen-producing cysts is a hallmark feature of the rare bone and endocrine disorder fibrous dysplasia/McCune-Albright syndrome.
A. Boyce +9 more
semanticscholar +1 more source
Advanced Science, EarlyView.This work summarizes the efficacy and mechanisms of probiotics in CRC treatment, providing a comprehensive overview of various encapsulation methods such as microcapsules, hydrogels, single‐cell nanocoatings, and nanofibers for targeted probiotic delivery to inflammatory sites, with particular emphasis on the potential advantages of emerging single ...
Hao Zhong +5 more
wiley +1 more source
A Pathology-Based Machine Learning Method to Assist in Epithelial Dysplasia Diagnosis [PDF]
arXiv, 2022 The Epithelial Dysplasia (ED) is a tissue alteration commonly present in lesions preceding oral cancer, being its presence one of the most important factors in the progression toward carcinoma. This study proposes a method to design a low computational cost classification system to support the detection of dysplastic epithelia, contributing to reduce ...
arxiv
Targeted Therapies in Myelofibrosis: Present Landscape, Ongoing Studies, and Future Perspectives
American Journal of Hematology, EarlyView.ABSTRACT Myelofibrosis (MF) is a myeloproliferative neoplasm that is accompanied by driver JAK2, CALR, or MPL mutations in more than 90% of cases, leading to constitutive activation of the JAK–STAT pathway. MF is a multifaceted disease characterized by trilineage myeloid proliferation with prominent megakaryocyte atypia and bone marrow fibrosis, as ...
Giuseppe G. Loscocco, Paola Guglielmelli
wiley +1 more source
Large Language Models for Granularized Barrett's Esophagus Diagnosis Classification [PDF]
arXiv, 2023 Diagnostic codes for Barrett's esophagus (BE), a precursor to esophageal cancer, lack granularity and precision for many research or clinical use cases. Laborious manual chart review is required to extract key diagnostic phenotypes from BE pathology reports. We developed a generalizable transformer-based method to automate data extraction.
arxiv
Increased Risk of Breast Cancer at a Young Age in Women with Fibrous Dysplasia
Journal of Bone and Mineral Research, 2018 Fibrous dysplasia (FD) is a rare bone disorder caused by mutations of the GNAS gene, which are also identified in malignancies. We explored the potential relationship between breast cancer and fibrous dysplasia in two fibrous dysplasia cohorts from the ...
B. Majoor +9 more
semanticscholar +1 more source
Clonal Hematopoiesis and Thrombosis
American Journal of Hematology, EarlyView.ABSTRACT Clonal hematopoiesis (CH) has been the focus of many research efforts in the last years and has emerged as a risk modifier for cardiovascular disease morbidity and mortality. While substantial evidence has accumulated regarding its impact on arterial system diseases, the connection with venous thrombosis has only recently been explored.
Cornelia Englisch, Cihan Ay
wiley +1 more source
Convolutional neural networks for automatic detection of Focal Cortical Dysplasia [PDF]
arXiv, 2020 Focal cortical dysplasia (FCD) is one of the most common epileptogenic lesions associated with cortical development malformations. However, the accurate detection of the FCD relies on the radiologist professionalism, and in many cases, the lesion could be missed.
arxiv
Undulation Instability of Epithelial Tissues [PDF]
Phys. Rev. Lett. 106, 158101 (2011), 2011 Treating the epithelium as an incompressible fluid adjacent to a viscoelastic stroma, we find a novel hydrodynamic instability that leads to the formation of protrusions of the epithelium into the stroma. This instability is a candidate for epithelial fingering observed in vivo.
arxiv +1 more source
Fibrous dysplasia of bone: craniofacial and dental implications.
Oral Diseases, 2017 Fibrous dysplasia (FD) is a rare bone disease caused by postzygotic somatic activating mutations in the GNAS gene, which lead to constitutive activation of adenylyl cyclase and elevated levels of cyclic AMP, which act on downstream signaling pathways and
A. Burke, Michael T. Collins, A. Boyce
semanticscholar +1 more source