Results 61 to 70 of about 298,062 (215)

Giant Fibrous Dysplasia of the Rib: A Case Report

Southern Clinics of Istanbul Eurasia, 2017
Fibrous dysplasia is a benign disease in which normal bone tissue is resorbed by fibrous tissue and immature bone structure. Fibrous dysplasia has been reported to account for approximately 5%–7% of all benign bone tumors; the rib involvement is rare ...
Semih Koçyiğit, Fatma Koçyiğit, Serpil Bayındır   +2 more
doaj   +1 more source

Growth hormone—Insulin‐like growth factor 1 axis hyperactivity on bone fibrous dysplasia in McCune‐Albright Syndrome

Clinical Endocrinology, 2018
In fibrous dysplasia (BFD), normal bone and bone marrow are replaced by fibro‐osseous tissue, leading to fracture, deformity and pain. BFD may be isolated, or in association with cutaneous hyperpigmentation and/or hyperfunctioning endocrinopathies ...
D. Tessaris, A. Boyce, M. Zacharin, P. Matarazzo, R. Lala, L. De Sanctis, M. Collins   +6 more
semanticscholar   +1 more source

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

Food Frontiers, EarlyView.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima, Parteek Prasher, Mousmee Sharma, Dietrich Büsselberg, Gabriela Figueroa‐González, Octavio Daniel Reyes‐Hernández, Edgar Yebrán Villegas‐Vázquez, Hernán Cortés, Gerardo Leyva‐Gómez, Jesús Herrera‐Bravo, Solomon Habtemariam, Javad Sharifi‐Rad, Monica Butnariu, Cristian Berar, Angela Caunii, William C. Cho   +15 more
wiley   +1 more source

Safety and Efficacy Findings From a Phase Ib/II Study of ASP‐1929 Photoimmunotherapy With Pembrolizumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background ASP‐1929 photoimmunotherapy—cetuximab conjugated to IRDye 700DX and red light (690 nm) for localized drug activation—results in rapid, selective cell killing. Methods This phase Ib/II open‐label study evaluated ASP‐1929 photoimmunotherapy plus pembrolizumab in patients with recurrent/metastatic HNSCC (≥ 1 accessible lesion, PD‐L1 ...
David M. Cognetti, Joseph M. Curry, Jennifer Johnson, Michael Kwon, Shirley Y. Su, Francisco Civantos, Coral Olazagasti, Joseph Valentino, Susanne M. Arnold, R. Bryan Bell, Michael K. Gibson, Kyle Mannion, Kathryn M. Van Abel, Katharine A. Price, Haiying Dong, Amy H. Thorne, Toshiaki Suzuki, Ann M. Gillenwater   +17 more
wiley   +1 more source

Different clinical presentation and management of temporal bone fibrous dysplasia in children

World Journal of Surgical Oncology, 2018
BackgroundFibrous dysplasia is a slowly progressive benign fibro-osseous disorder that involves one or multiple bones with a unilateral distribution in most cases.
J. Mierzwiński, Justyna Kosowska, J. Tyra, Karolina Haber, M. Drela, D. Pączkowski, P. Burduk   +6 more
semanticscholar   +1 more source

Biomedical Applications of 3D‐Printed Polyamide: A Systematic Review

Macromolecular Materials and Engineering, EarlyView.
Additive manufacturing expands possibilities for personalized biomedical solutions, emphasizing the role of material science. This review examines the mechanical properties of 3D printed polyamide and explores its advantages and limitations in biomedical applications, including personalized implants, medical devices, and patient‐specific tools, as well,
Emese Paari‐Molnar, Wa'el Nafith Abdel‐Fattah Qa'dan, Kinga Kardos, Roland Told, Nitin Sahai, Peter Varga, Szilard Rendeki, Gabor Szabo, Kata Fekete, Tihamer Molnar, Adam Tibor Schlegl, Peter Maroti, Luca Toth   +12 more
wiley   +1 more source

Flexible Cervical Photodynamic Therapy Device

Translational Biophotonics, EarlyView.
This paper aims to design a flexible photodynamic therapy device for the cervix and cervical vault, using an LED array, light guide, and flexible trumpet‐shaped homogenizer. Simulations and tests show output irradiance up to 98 mW/cm2 with < 14.2% variation, offering a low‐cost solution for cervical cancer and precancerous lesions.
Teng Jin, Yijia Li, Qin Li, Xiaoming Hu, Jun Zhang, Lianmei Luo   +5 more
wiley   +1 more source

Individualized approach to the surgical management of fibrous dysplasia of the proximal femur

Orphanet Journal of Rare Diseases, 2018
BackgroundFibrous dysplasia of the proximal femur presents with heterogeneous clinical manifestations dictating different surgical approaches. However, to date there are no clear recommendations to guide the choice of surgical approach and no general ...
B. Majoor, A. Leithner, M. V. D. van de Sande, N. Appelman‐Dijkstra, N. Hamdy, P. Dijkstra   +5 more
semanticscholar   +1 more source

Surgical ankylosis of the radioulnar joint to manage chronic medial coronoid disease in dogs

Veterinary Record Case Reports, EarlyView.
Abstract In this small pilot study, we describe a new surgical technique, ankylosis of the radioulnar joint, in managing chronic persistent lameness in three dogs with medial coronoid disease. Computed tomography and arthroscopic elbow joint re‐evaluation were performed before surgical ankylosis of the radioulnar joint.
Thomas A. Niedenführ, Lars F. H. Theyse
wiley   +1 more source

Clival fibrous dysplasia in which short interval disease progression posed a diagnostic challenge in a skeletally mature patient: a case report

Journal of Medical Case Reports
Background Fibrous dysplasia is an uncommon bone disorder in which medullary bone is replaced by disorganized fibro-osseous tissue. Fibrous dysplasia typically exhibits slow growth that stabilizes with skeletal maturity.
Sujitra Tinnut, Nancy Pham, Jayakar Nayak, Juan C. Fernandez-Miranda, Hannes Vogel, Nancy Fischbein   +5 more
doaj   +1 more source