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Fibrous dysplasia is an ailment , that can include , one or a few bones and is portrayed by bone deformations, pain and fractures, arising due to bone weakening. A few patients can also present with endocrine dysfunction ( precocious puberty) and cutaneous cafe '- au - lait spots.[1] Determination depends on X-ray assessment.
Ampalaya Manu R+3 more
openaire +1 more source
Fibrous Dysplasia / McCune Albright syndrome (FD/MAS) represents a wide spectrum of diseases due to somatic gain-of-function mutations of the GNAS gene. The mutation leads to overactivity in the target tissues and to a wide phenotype of clinical features
Muhammad Kassim Javaid+20 more
doaj +1 more source
Biomimetic peptide enriched nonwoven scaffolds promote calcium phosphate mineralisation [PDF]
Cell-free translational strategies are needed to accelerate the repair of mineralised tissues, particularly large bone defects, using minimally invasive approaches. Regenerative bone scaffolds should ideally mimic aspects of the tissue's ECM over multiple length scales and enable surgical handling and fixation during implantation in vivo.
arxiv +1 more source
The original version of this article [1] unfortunately included an error to an author’s name. Paul Arundel was inadvertently presented as Paul Arunde.
Muhammad Kassim Javaid+20 more
doaj +1 more source
Tibial fibrous dysplasia in children treated by Ilizarov technique – a review of treatment options
Fibrous dysplasia is a pathological condition, where normal medullary bone is replaced by fibrous tissue and small woven specules of bone. Fibrous dysplasia can occur in epiphysis, metaphysis or diaphysis.
Mofakhkharul M. Bari+3 more
doaj +1 more source
Fibrous dysplasia is a developmental disorder of the bone that originates from a genetic defect disturbing the osteogenesis leading to the replacement of normal bone with the excess proliferation of fibrous tissue.
Antoine Berberi+3 more
doaj +1 more source
Dysplasia grading of colorectal polyps through CNN analysis of WSI [PDF]
Colorectal cancer is a leading cause of cancer death for both men and women. For this reason, histopathological characterization of colorectal polyps is the major instrument for the pathologist in order to infer the actual risk for cancer and to guide further follow-up.
arxiv +1 more source
Fibrous dysplasia of sphenoid bone presenting as a case of loss of vision
Background: Fibrous dysplasia is a fibro-osseous lesion of unclear aetiology wherein normal bone is replaced by abnormal fibrous tissue and immature bone.
Abhishek Katyal, Daljit Singh
doaj
Frontal bone fibrous dysplasia in a 6-months-old boy: A distinctive entity
Fibrous Dysplasia (FD) is a non-malignant condition caused by post-zygotic, activating mutations of the GNAS gene that results in inhibition of the differentiation and proliferation of bone-forming stromal cells and leads to the replacement of normal ...
Kleanthis Anastasiadis+5 more
doaj +1 more source
The influence of bone surface availability in bone remodelling - A mathematical model including coupled geometrical and biomechanical regulations of bone cells [PDF]
Bone is a biomaterial undergoing continuous renewal. The renewal process is known as bone remodelling and is operated by bone-resorbing cells (osteoclasts) and bone-forming cells (osteoblasts). Both biochemical and biomechanical regulatory mechanisms have been identified in the interaction between osteoclasts and osteoblasts.
arxiv +1 more source