Results 41 to 50 of about 11,860 (185)

Phytochemical‐Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles

Phytotherapy Research, EarlyView.
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam, Abdur Rauf, Happy Akter, Md. Ibrahim Khalil Al‐Imran, Md. Naeem Hossain Fakir, Gazi Kaifeara Thufa, Umme Habiba, Karjin Nahar Riya, Md. Mahfuzur Rahman, Md Sadique Hussain, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Dorota Formanowicz, Marcello Iriti   +14 more
wiley   +1 more source

Protein kinase A is a dependent factor and therapeutic target in mouse models of fibrous dysplasia

Nature Communications
Fibrous dysplasia is a skeletal disorder caused by activating mutations in Gαs, leading to bone fractures, deformities, and pain. Protein kinase A (PKA), the principal effector of Gαs, plays critical roles in various biological processes.
Zhongyu Liu, Lu Xing, Wenlong Huang, Ning Ji, Hang Zhao, Qianming Chen, Xianglong Han, Ding Bai, Xuefeng Zhao   +8 more
doaj   +1 more source

Fibrous Dysplasia: Clinicopathologic Presentation of 36 Cases

Türk Patoloji Dergisi, 2018
Objective: Fibrous dysplasia is a slowly progressing bone lesion resulting from displacement of the normal medullary bone with abnormal fibroosseous tissue.
Mine ÖZŞEN, Ülviye YALÇINKAYA, Muhammed Sadık BILGEN, Zeynep YAZICI   +3 more
doaj   +1 more source

Pseudotumoral fibrous dysplasia of the maxilla

Indian Journal of Radiology and Imaging, 2005
Fibrous dysplasia is a skeletal disorders of unknown etiology usually affecting the young. Women are commonly affected more than men. Craniofacial fibrous dysplasia can have a varied presentation.
AT Kharat, A Singh, VM Kulkarni, S Omar
doaj   +1 more source

Clinical Challenges in Transition to Adult Care for Young People With Endocrinopathies

Clinical Endocrinology, EarlyView.
ABSTRACT The complexity of transition of pediatric patients to adult care is well recognized, with a multidisciplinary approach widely agreed to be essential. Despite extensive existing literature in this area, practical guidance as to the management of specific medical aspects and how to address these with patients and families is lacking, with little
Margaret Zacharin, Quynh‐Nhu Nguyen
wiley   +1 more source

Examining the Role of Artificial Intelligence in Assessment: A Comparative Study of ChatGPT and Educator‐Generated Multiple‐Choice Questions in a Dental Exam

European Journal of Dental Education, EarlyView.
ABSTRACT Aim To compare the item difficulty and discriminative index of multiple‐choice questions (MCQs) generated by ChatGPT with those created by dental educators, based on the performance of dental students in a real exam setting. Materials and Methods A total of 40 MCQs—20 generated by ChatGPT 4.0 and 20 by dental educators—were developed based on ...
Nezaket Ezgi Özer, Yusuf Balcı, Gaye Bölükbaşı, Betul İlhan, Pelin Güneri   +4 more
wiley   +1 more source

Maxillofacial fibrous dysplasia

Indian Journal of Dental Research, 2005
Fibrous dysplasia is a non- neoplastic hamartomatous developmental fibro osseous lesion of bone. This paper provides a brief overview of fibrous dysplasia in a historic perspective and highlights the controversies in fibrous dysplasia seen in the cranio-
Mahajan Sumita, Kamboj Mala, Baoz Karen
doaj  

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

Changes in the 6th edition of the World Health Organization classification of tumours of the digestive system

Histopathology, EarlyView.
Changes and new entities in the 6th edition WCT of the digestive system, including structural, molecular, and diagnostic updates to standardize terminology and improve clinical relevance. Epithelial tumours are organized by site; neuroendocrine, mesenchymal and haematolymphoid tumours have dedicated chapters, with refined grading, redefined ...
Mark J Arends, Irene Esposito, Anthony J Gill, Ralph H Hruban, Joseph D Khoury, Motohiro Kojima, Elizabeth A Montgomery, Fatimah Abdulkareem, Fátima Carneiro, Guido Costamagna, Gregory Lauwers, Alexandros D Polydorides, Guido Rindi, Massimo Rugge, Peter Schirmacher, Amitabh Srivastava, James Yao, Jennelle C Hodge, James G Kench, Bharat Rekhi, Miguel Reyes‐Múgica, Antonia R Sepulveda, Chanjuan Shi, Pavitratha Puspanathan, Harshima Wijesinghe, Christine Giesen, Blanca Iciar Indave Ruiz, Dilani Lokuhetty, WCT standing editorial board, Iris D Nagtegaal, Wendy Cooper, Michael Eden, Andrew Field, Vicky Goh, Jennelle Hodge, James Kench, Joseph Khoury, Katia Leite, Zhiyong Liang, Daichi Maeda, George Netto, Bharat Rekhi, Miguel Reyes Múgica, Brian Rous, Ales Ryska, Shahin Sayed, Antonia R Sepulveda, Chanjuan Shi, Gary Tse   +48 more
wiley   +1 more source

A Rare Case of Radiculopathy: Monostotic Fibrous Dysplasia of the Sacrum

Acta Médica Portuguesa, 2019
Fibrous dysplasia is a bone disease characterized by an osteoblastic dysfunction resulting in a fibrous replacement of the normal medullary bone. We describe the case of a 33-year-old who presented with low back pain irradiating to her right leg.
Joaquim Cruz Teixeira, Diogo Cardoso Simão, José Pimentel, Sérgio Livraghi   +3 more
doaj   +1 more source