Results 41 to 50 of about 241,790 (262)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Myofibroblasts and Transforming Growth Factor-Beta1 in Reactive Gingival Overgrowths

eJournal of Oral Maxillofacial Research, 2013
Objectives: The aim of this study was to detect the presence of myofibroblasts and transforming growth factor-beta1 in fibrous and ossifying-fibrous epulis and their possible contribution to the collagenous connective tissue formation.
Apostolos Epivatianos, Dimitrios Andreadis, Savas Iordanidis   +2 more
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Polyostotic fibrous dysplasia without craniofacial involvement: An unusual presentation

Journal of the Scientific Society, 2018
Fibrous dysplasia (FD) is a benign bone disorder resulting into the replacement of bone with fibrous tissue. These fibrous bones are prone for deformities, pain, and pathological fractures, hence requiring treatment.
Seema Sharma, Milap Sharma, Parvinder Singh, Vipin Sharma   +3 more
doaj   +1 more source

Tibial fibrous dysplasia in children treated by Ilizarov technique – a review of treatment options

Гений oртопедии, 2021
Fibrous dysplasia is a pathological condition, where normal medullary bone is replaced by fibrous tissue and small woven specules of bone. Fibrous dysplasia can occur in epiphysis, metaphysis or diaphysis.
Mofakhkharul M. Bari, Islam Shahidul, Ashraf Tanvir, A.M. Shayan R. Bari   +3 more
doaj   +1 more source

Fibrous proteins and tissue engineering

Materials Today, 2006
Fibrous proteins are finding broad impact in biomaterial systems for a range of cell and tissue studies. This impact derives from an improved insight into fundamental structure-function relationships, as well as the unique material properties attained with these protein polymers.
Wang, Xianyan, Kim, Hyeon Joo, Wong, Cheryl, Vepari, Charu, Matsumoto, Akira, Kaplan, David L.   +5 more
openaire   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Biomimicry, biomineralization, and bioregeneration of bone using advanced three-dimensional fibrous hydroxyapatite scaffold

Materials Today Advances, 2019
Biomimicry, biomineralization, and bioregeneration technologies will pave the way for regenerative medicine toward better human health. Functional fibrous scaffold with extracellular matrix–like natural structure and the three-dimensional (3D) network is
Z. Li, D. Chu, Y. Gao, L. Jin, X. Zhang, W. Cui, J. Li   +6 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source