Results 61 to 70 of about 2,068,297 (300)

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Transformations of respiratory epitelium in fibrous stage of acute respiratory distress-syndrome = Трансформация респираторного эпителия в фазу фиброза острого респираторного дистресс-синдрома [PDF]

, 2014
Novikov Nikolay, Tumansky Valery, Fedotov Vasiliy. transformations of respiratory epitelium in fibrous stage of acute respiratory distress-syndrome = Трансформация респираторного эпителия в фазу фиброза острого респираторного дистресс-синдрома.
Fedotov, Vasiliy, Novikov, Nikolay, Tumansky, Valery   +2 more
core   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Fibrous scaffolds for tissue engineering

Inflammation and Regeneration, 2014
Scaffold, along with seed cells and microenvironment, is an essential component of tissue engineering, and plays an important role in engineered tissue regeneration. Fibrous scaffold is an important part of scaffold materials due to its ability to mimic the structure of native extracellular matrix.
Shi, Yuan, Wang, Yingchu, Zhang, Peihua, Liu, Wei   +3 more
openaire   +2 more sources

European Society of Biomechanics SM Perren Award 2010 : an adaptation mechanism for fibrous tissue to sustained shortening

, 2010
The mechanism by which fibrous tissues adapt upon alterations in their mechanical environment remains unresolved. Here, we determine that periosteum in chick embryos resides in an identical mechanical state, irrespective of the developmental stage.
Donkelaar, van, C.C., Ito, K Keita, Foolen, J., Foolen, J.; id_orcid, Donkelaar, CC René van, Soekhradj - Soechit, R.S., Sarita Soekhradj-Soechit, Keita Ito, Foolen, J Jasper, Corrinus C. van Donkelaar, Jasper Foolen, Ito, K., Soekhradj - Soechit, RS Sarita   +12 more
core   +1 more source

Fibrous scaffolds for bone tissue engineering

, 2020
More than 1 million orthopedic procedures are performed in the U.S. each year, for reconstructive surgery, trauma, or abnormal skeletal defects. Bone grafts are typically used in these procedures.
Apurva Limaye, Treena Livingston Arinzeh, Moy, Jennifer, Limaye, Apurva, Jennifer Moy, Arinzeh, Treena Livingston   +5 more
core   +1 more source

Temporal effects of mechanical loading on deformation-induced damage in skeletal muscle tissue [PDF]

, 2010
Mechanical loading of soft tissues covering bony prominences can cause skeletal muscle damage, ultimately resulting in a severe pressure ulcer termed deep tissue injury.
S. Loerakker, Bader, D.L., Rijpkema, JJM Koo, K. Nicolay, Baaijens, F. P. T., C. W. J. Oomens, Strijkers, GJ Gustav, Oomens, CWJ Cees, Loerakker, S., Oomens, C.W.J., Nicolaij, K Klaas, Strijkers, G. J., Baaijens, FPT Frank, Rijpkema, J. J. M., Stekelenburg, A., G. J. Strijkers, Strijkers, G.j., Oomens, C. W. J., Loerakker, S Sandra, Stekelenburg, A Anke, D. L. Bader, Baaijens, F.P.T., Rijpkema, J.J.M., Bader, D. L., J. J. M. Rijpkema, F. P. T. Baaijens, Bader, DL Dan, A. Stekelenburg, Nicolay, K.   +28 more
core   +2 more sources

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source