Results 31 to 40 of about 8,146 (276)

Towards Cognitive Moral Quasi-Realism

Philosophies, 2018
There is a long-standing discussion concerning the nature of moral discourse. Multiple views range from realism—according to which moral discourse is closer to scientific discourse than to fictional discourse—to anti-realism—according to which moral ...
Eduardo García-Ramírez
doaj   +1 more source

The Alethic Status of Contradictions in Fictional Discourse [PDF]

Organon F
Whether contradictions could be “true in fiction” has become an unavoidable topic in the debates on the bounds of fictionality. This paper claims that genuine contradictions in fiction are far more infrequent phenomena than is usually claimed.
Vladimir Vujošević
doaj   +1 more source

Eye-movements and ERPs reveal the time course of processing negation and remitting counterfactual worlds [PDF]

, 2008
The ability to update our current knowledge using contextual information is a vital process during every-day language comprehension. To understand a negated statement, readers are required to cancel real-world expectations, but are not explicitly ...
Ferguson, Heather J., Sanford, Anthony J., Leuthold, Hartmut   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

The Contextual Semantic Realization of the Lexical Units Hesitate, Waver, Vacillate, Falter vs. Hesitation, Hesitancy

East European Journal of Psycholinguistics, 2017
This article is dedicated to the research of synonymous groups for the designation of doubt “Hesitate, Waver, Vacillate, Falter” and “Hesitation, Hesitancy” in contemporary English-language fictional discourse.
Alla Gnatiuk
doaj   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

The Role of Extralingual Factors in Shaping Interpersonal Conflict in Modern English Fictional Discourse [PDF]

Alfred Nobel University Journal of Philology
The article investigates the role of extralingual factors in shaping and developing interpersonal conflict in contemporary English fictional discourse.
Olha Chernenko
doaj   +1 more source

The Detection and Understanding of Fictional Discourse

CoRR
In this paper, we present a variety of classification experiments related to the task of fictional discourse detection. We utilize a diverse array of datasets, including contemporary professionally published fiction, historical fiction from the Hathi Trust, fanfiction, stories from Reddit, folk tales, GPT-generated stories, and anglophone world ...
Andrew Piper, Haiqi Zhou
openaire   +2 more sources

Mitigation strategies of promise and request in English fictional discourse

, 2022
Анотація. Мета статті полягає в контекстуально-інтерпретаційному аналізі мітігативних стратегій обіцянки та прохання, якими керуються персонажі англомовного художнього дискурсу.
Dede, Yuliia V., Деде, Юлія Володимирівна   +1 more
core   +1 more source