Results 41 to 50 of about 467 (170)

Specific Binding Peptides from Rv3632: A Strategy for Blocking Mycobacterium tuberculosis Entry to Target Cells?

BioMed Research International, Volume 2019, Issue 1, 2019., 2019
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis (Mtb, i.e., the aetiological agent); the WHO has established this disease as high priority due to its ensuing mortality. Mtb uses a range of mechanisms for preventing its elimination by an infected host; new, viable alternatives for blocking the host‐pathogen interaction are ...
Christian David Sánchez-Barinas, Marisol Ocampo, Luisa Tabares, Maritza Bermúdez, Manuel Alfonso Patarroyo, Manuel Elkin Patarroyo, Rita Casadio   +6 more
wiley   +1 more source

Mass & secondary structure propensity of amino acids explain their mutability and evolutionary replacements

Scientific Reports, 2017
Why is an amino acid replacement in a protein accepted during evolution? The answer given by bioinformatics relies on the frequency of change of each amino acid by another one and the propensity of each to remain unchanged.
Hugo J. Bohórquez, Carlos F. Suárez, Manuel E. Patarroyo   +2 more
doaj   +1 more source

Comprehensive review of innovative construction technology of high‐core rockfill dam: Nuozhadu project

River, Volume 4, Issue 2, Page 135-148, May 2025.
Abstract Underpinned by the ultrahigh‐core rockfill dam at the Nuozhadu Hydropower Station, comprehensive studies and engineering practices have been conducted to address several critical challenges: coordination of seepage deformation in dam materials, prevention and control of high‐water‐pressure seepage failure, static and dynamic deformation ...
Biao Liu, Zongliang Zhang, Lei Yan, Chao Liu, Mingxin Wu, Yuzhen Yu, Daren Zhang   +6 more
wiley   +1 more source

Quantitative Entropy Weight TOPSIS Evaluation of Sustainable Chinese Wind Power Developments

Mathematical Problems in Engineering, Volume 2018, Issue 1, 2018., 2018
Based on a Driving Forces‐Pressure‐State‐Impact‐Response (DPSIR) model, this paper takes a macroenvironmental, socioeconomic perspective to build an evaluation model to address sustainable Chinese wind power developments and to quantize the development results. From a combination of entropy weight and the Technique for Order of Preference by Similarity
Hongyan Zheng, Dongyang Si, Wei Wang, Ruining Wang, Gilberto Espinosa-Paredes   +4 more
wiley   +1 more source

A Bibliometric Review on Risk Management and Building Information Modeling for International Construction

Advances in Civil Engineering, Volume 2018, Issue 1, 2018., 2018
International construction is complicated and involves high risks. However, with the development of technological innovation, Building Information Modeling (BIM) emerged and seems to be able to address certain risks. To understand BIM applications in risk management for international construction, a state‐of‐the‐art review is required.
Tsenguun Ganbat, Heap-Yih Chong, Pin-Chao Liao, You-Di Wu, Xianbo Zhao   +4 more
wiley   +1 more source

Role of Histone Demethylases in Cardiomyocytes Induced to Hypertrophy

BioMed Research International, Volume 2016, Issue 1, 2016., 2016
Epigenetic changes induced by histone demethylases play an important role in differentiation and pathological changes in cardiac cells. However, the role of the jumonji family of demethylases in the development of cardiac hypertrophy remains elusive.
Wendy Rosales, Juan Carulla, Jeison García, Diana Vargas, Fernando Lizcano, Wen-Hwa Lee   +5 more
wiley   +1 more source

Mycobacterium tuberculosis H37Rv LpqG Protein Peptides Can Inhibit Mycobacterial Entry through Specific Interactions

Molecules, 2018
Mycobacterium tuberculosis is the causative agent of tuberculosis, a disease causing major mortality worldwide. As part of a systematic methodology for studying M.
Christian David Sánchez-Barinas, Marisol Ocampo, Magnolia Vanegas, Jeimmy Johana Castañeda-Ramirez, Manuel Alfonso Patarroyo, Manuel Elkin Patarroyo   +5 more
doaj   +1 more source

Modulating p56Lck in T‐Cells by a Chimeric Peptide Comprising Two Functionally Different Motifs of Tip from Herpesvirus saimiri

Journal of Immunology Research, Volume 2015, Issue 1, 2015., 2015
The Lck interacting protein Tip of Herpesvirus saimiri is responsible for T‐cell transformation both in vitro and in vivo. Here we designed the chimeric peptide hTip‐CSKH, comprising the Lck specific interacting motif CSKH of Tip and its hydrophobic transmembrane sequence (hTip), the latter as a vector targeting lipid rafts. We found that hTip‐CSKH can
Jean-Paul Vernot, Ana María Perdomo-Arciniegas, Luis Alberto Pérez-Quintero, Diego Fernando Martínez, Darren R. Flower   +4 more
wiley   +1 more source

A Project Management Approach to a Highway Construction in Montenegro [PDF]

European Project Management Journal, 2017
The management of design and build contract for Bar-Boljare highway construction section Smokovac-Uvač-Mateševo is based on FIDIC conditions of the Contracting and introduces new standards in the system of managing and implementation of large ...
Sanja Međedović, Michael Ellis
doaj  

Iskustva u primjeni FIDIC-ovih ugovora kod projekata željezničke infrastrukture

Građevinar, 2019
U radu se razmatra primjena FIDIC-ovih općih uvjeta ugovora u izvođenju radova na izgradnji željezničke infrastrukture. Analiziraju se ugovorna ograničenja kao što su: minimalni iznos situacije, predujam i dinamika vraćanja predujma, garancije i zadržana
Edvin Bralić
doaj   +1 more source