Results 211 to 220 of about 12,921 (254)

Correction of Ineffective Erythropoiesis and Normalization of Iron Homeostasis After Exagamglogene Autotemcel in Transfusion‐Dependent β‐Thalassemia

American Journal of Hematology, Volume 101, Issue 8, Page 1969-1979, August 2026.
ABSTRACT Exagamglogene autotemcel (exa‐cel) is a one‐time, ex vivo, CRISPR‐Cas9 gene edited cell therapy approved for patients with transfusion dependent β‐thalassemia (TDT) aged 12–35 years. In a Phase 3 study (CLIMB THAL‐111), exa‐cel treatment resulted in reactivation of fetal hemoglobin and increases in total hemoglobin, leading to transfusion ...
Sujit Sheth, Selim Corbacioglu, Josu de la Fuente, Mattia Algeri, Joachim Rupprecht, Kevin H. M. Kuo, Ami J. Shah, Peter Lang, Hayley Merkeley, Ben Carpenter, Markus Y. Mapara, Robert I. Liem, Stephan Grupp, Yogi Chopra, Amanda M. Li, Janet L. Kwiatkowski, Melanie Kirby‐Allen, Maria Domenica Cappellini, Antonis Kattamis, Sakellarios Zairis, Tina Liu, William Hobbs, Haydar Frangoul, Franco Locatelli, Roland Meisel, on behalf of the CLIMB THAL‐111 and CLIMB‐131 Study Groups   +25 more
wiley   +1 more source

Understanding the Workflows in Dynamic and Robotic Computer‐Assisted Implant Surgery

Clinical and Experimental Dental Research, Volume 12, Issue 4, August 2026.
ABSTRACT Computer‐assisted implant surgery (CAIS) represents a comprehensive digital workflow integrating prosthetically driven planning with various execution modalities. Among these, dynamic (d‐CAIS) and robotic (r‐CAIS) systems constitute two distinct yet interrelated approaches, sharing core technological principles as well as operative differences.
Adria Jorba‐Garcia, Shengchi Fan, Feng Wang, James Chow, Atiphan Pimkhaokham, Nikos Mattheos, Alessandro Pozzi   +6 more
wiley   +1 more source

Mechanisms Underlying Pain Avoidance in Complex Regional Pain Syndrome

European Journal of Pain, Volume 30, Issue 7, August 2026.
ABSTRACT Background Maladaptive pain avoidance plays a critical role in chronic pain development and maintenance. Pain avoidance reinforced instrumentally through action‐outcome contingencies remains poorly understood, specifically in complex regional pain syndrome (CRPS), a nociplastic condition.
Raghavan Gopalakrishnan, Nitesh Singh Malan, Claire Sonneborn, Olivia Hogue, Pavan Tankha, Sylvain Baillet, Mathieu Roy   +6 more
wiley   +1 more source

First‐line treatment with epcoritamab in combination with bendamustine plus rituximab induces sustained remissions beyond 3 years in patients with follicular lymphoma

HemaSphere, Volume 10, Issue 8, August 2026.
Abstract First‐line (1L) bendamustine plus rituximab (BR) leads to high response rates in follicular lymphoma (FL), but maintaining durable remissions remains challenging. We report the 3‐year follow‐up from arm 3 of the phase 1b/2 EPCORE NHL‐2 trial (NCT04663347) of epcoritamab, a subcutaneously administered CD3×CD20 bispecific antibody, combined with
Umberto Vitolo, Lorenzo Falchi, Per‐Ola Andersson, Marcel Nijland, Fritz Offner, Sylvia Snauwaert, Jacob H. Christensen, Michael R. Clausen, Alexander Fosså, Pilar G. Prieto, Eliza A. Hawkes, Judit M. Jørgensen, Yasmin H. Karimi, Catharina Lewerin, Joost S. P. Vermaat, Björn E. Wahlin, Poliana Patah, Christopher Morehouse, Malene Risum, Zhu Li, Jennifer Marek, Joshua D. Brody   +21 more
wiley   +1 more source

Impact of Leaflet Thickness on Polymeric Valve Scaffold Function and Remodeling: Assessment in a 1‐ and 3‐Month Ovine Stented Pulmonary Valve Replacement Model

Journal of Biomedical Materials Research Part A, Volume 114, Issue 8, August 2026.
ABSTRACT Approaches to the structural design of tissue engineered heart valves (TEHVs) have varied broadly, ranging from material choice to microstructural and macro‐scale functional characteristics. Not only will each variable on this extensive list impact functional and restorative potential after implantation, but most of these variables also have ...
Drake D. Pedersen, Garrett Coyan, Viktor Balashov, Arianna Adamo, Patrizia Caruso, Flaviana Falci, Vesselin Shanov, William E. Katz, David Kokot, Giuseppe D'Ancona, William R. Wagner, Antonio D'Amore   +11 more
wiley   +1 more source

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Speeded up detection of squared fiducial markers

Image and Vision Computing, 2018
Squared planar markers have become a popular method for pose estimation in applications such as autonomous robots, unmanned vehicles and virtual trainers. The markers allow estimating the position of a monocular camera with minimal cost, high robustness, and speed.
Rafael Muñoz-Salinas, FRANCISCO J Romero-Ramírez, Rafael Medina-Carnicer   +2 more
exaly   +3 more sources

Fiducial Markers for Pose Estimation

Journal of Intelligent and Robotic Systems: Theory and Applications, 2021
Brennan Cain, Nikolaos Vitzilaios
exaly   +3 more sources

Marker orientation in fiducial registration

SPIE Proceedings, 2003
Fiducial markers are often employed in image-guided surgical procedures to provide positional information based on pre-operative images. In the standard technique, centroids of three or more markers are localized in both image space and physical space. The localized positions are used in a closed-form algorithm to determine the three-dimensional rigid ...
Xiaofeng Liu, Hakan Cevikalp, J. Michael Fitzpatrick   +2 more
openaire   +1 more source

Quantification of projective distortion for fiducial markers

2013 21st Signal Processing and Communications Applications Conference (SIU), 2013
The aim of this study is to quantify the projective distortion of candidate quadrilaterals found in a square-framed fiducial marker detection algorithm. Based on the quantified value, candidates can be eliminated in such a way that only the quadrilaterals that may be a projective transformation of a square remain.
Burak Benligiray, Cihan Topal, Cuneyt Akinlar, Yakup Genc   +3 more
openaire   +2 more sources

Embedding prolene for the development of fiducial markers

The Anatomical Record, 1989
AbstractA simple, inexpensive method is described for embedding Prolene with tissue samples to provide landmarks for fiducial points to align serial sections in tissue reconstructions. Prolene is a monofilament suture material that can be easily sectioned with diamond knives to provide circular markers in each section.
C L, Johnson, R A, Underwood, K A, Holbrook   +2 more
openaire   +2 more sources