Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Terminator field‐aligned currents: A new finding from the Ionospheric Dynamics and Electrodynamics Data Assimilation Model [PDF]
L. Zhu +5 more
openalex +1 more source
Generation of Field‐Aligned Currents During Substorm Expansion: An Update [PDF]
Yusuke Ebihara, Takashi Tanaka
openalex +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Field‐aligned currents (FACs) are the main physical mechanism behind magnetosphere–ionosphere coupling, with these currents communicating environmental changes between the two regions of geospace.
Martin O. Archer +6 more
doaj +1 more source
Effect of Interhemispheric Field-Aligned Currents on Region-1 Currents [PDF]
An asymmetry in ionospheric conductivity between two hemispheres results in the formation of additional, interhemispheric field-aligned currents flowing between conjugate ionospheres within two auroral zones.
Khazanov, George V. +2 more
core +1 more source
Field-Aligned Current Mechanisms of Prominence Destabilization [PDF]
Solar wind is initiated from active solar flare regions. Solar flares start with an active-region prominence: cold dense plasma associated with an arcade of looped magnetic field lines. A prominence can be stable for hours or days but sometimes it takes on a violent evolution: as the magnetic field structure slowly evolves, the loop becomes more and ...
openaire +2 more sources
Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
Investigation of MAGSAT and TRIAD magnetometer data to provide corrective information on high-lattitude external fields [PDF]
Disturbances in the MAGSAT magnetometer data set due to high latitude phenomena were evaluated. Much of the categorization of disturbances due to Birkeland currents, ionospheric Hall currents, fine structure and wave phenomena was done with the MAGSAT ...
Potemra, T. A. +2 more
core +1 more source
Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati +10 more
wiley +1 more source

