Results 41 to 50 of about 5,931,505 (319)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Genotype and Phenotype Interaction between OsWKRYq6 and BLB after Xanthomonas oryzae pv. Oryzae Inoculation in the Field

open access: yesPlants, 2022
Bacterial leaf blight (BLB) is an important and devastating rice disease caused by the pathogen Xanthomonas oryzae pv. Oryzae (Xoo). In particular, in recent years, the occurrence of abnormal climate and warming phenomena has produced a good environment ...
Xiao-Xuan Du   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Religious Freedom, Governance of Religious Diversity, and Interreligious Dialogue: The Case of Turin

open access: yesReligions
Religious freedom, the management of religious diversity, and interreligious dialogue are emerging and closely interconnected phenomena. In the context of increasing religious pluralism, policymakers, religious institutions, and other civil society ...
Matteo Di Placido, Stefania Palmisano
doaj   +1 more source

Drilling challenges and technological solutions in the development of oil deposits in fractured carbonate reservoirs [PDF]

open access: yesНанотехнологии в строительстве
Introduction. Currently, carbonate reservoirs play an increasingly significant role in the global hydrocarbon balance. Most of the deposits discovered in recent years are fractured carbonate reservoirs.
Alexander V. Melnikov   +3 more
doaj   +1 more source

Heavy Metal Contamination on Shallot Fields In Bantul Regency, Yogyakarta

open access: yesJournal of Tropical Soils, 2021
Shallot cultivation usually uses very intensive agrochemicals that could affect the soil’s chemical properties and contaminate agricultural land by increasing the content of heavy metals.
Cicik Oktasari Handayani   +2 more
doaj   +1 more source

Fields over Fields

open access: yesinSTEMM Journal, 2022
We investigate certain arithmetic properties of field theories. In particular, we study the vacuum structure of supersymmetric gauge theories as algebraic varieties over number fields of finite characteristic. Parallel to the Plethystic Programme of counting the spectrum of operators from the syzygies of the complex geometry, we construct, based on the
openaire   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

La pratique de terrain d’un géographe moderne, Albert Demangeon (1872-1940)

open access: yesBelgeo, 2013
While geographers of previous generations were specialists of historical geography, which is (exclusively) geography carried out from the study, Paul Vidal de la Blache and his followers were ardent promoters of fieldwork geography.
Denis Wolff
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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