Results 61 to 70 of about 11,312,036 (276)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Hospitalization of Field Museum

open access: yes, 1918
Memorandum specification completed by the architectural firm Graham, Anderson, Probst and White for the trustees of the Field Museum. The specification was developed to outline the construction and finishing work for converting the existing ...
Graham, Anderson, Probst and White
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

DOMINASI HABITUS DALAM PRAKTIK KHITAN PEREMPUAN DI DESA KUNTU DARUSSALAM KABUPATEN KAMPAR RIAU (Aplikasi Praktik Sosial Pierre Boudieu dalam Living Hadis)

open access: yesJurnal Living Hadis, 2016
Understanding common sense surrounding society where people act according to their interpretation toward hadith of the prophet as well Qur’anic verses and command is an essential meaning of living hadith.
Hikmalisa Hikmalisa
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Le hasard peut-il bien faire les choses ?

open access: yesSociologies, 2013
Through two examples of field experiences related to our doctoral research, one in anthropology with cocaine users said to be "hidden" or integrated, the other in geography and regarding migrations from sub-Saharan Africa to Turkey, we intend to discuss ...
Aude Wyart, Nicolas Fait
doaj  

The Reconfiguration of the Theatre Space and the Relationship between Public and Private in the Case of Apartment Theatre

open access: yesRomanian Journal of Communications and Public Relations, 2017
This article tackles the means of theatre space reconfiguration in the apartment theater (lorgean theater), simultaneously analyzing the relation between public and private specific to this form of art.
Andreea Gabriela Lupu
doaj   +1 more source

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