Results 91 to 100 of about 11,082,968 (347)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

ABERRANT DATA IN FIELD EXPERIMENTS

open access: yesExperimental Agriculture, 2000
A field experiment will sometimes give data so unexpected that their correctness is doubted. It would be wrong to discard them because they go against the experimenter's preconceptions but sometimes enquiry will reveal why they are aberrant. Sometimes no reason can be found but they still raise doubts.
Dyke, G. V., Pearce, S. C.
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Near-field imaging with far-field data

open access: yesApplied Mathematics Letters, 2016
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Gang Bao, Peijun Li, Yuliang Wang
openaire   +1 more source

Comparing the EPA Indoor Air Quality Personal Computer Model and Field Data [PDF]

open access: yes, 2000
The authors recommend caution in using an EPA model for reconstructing past exposure events as well as for predicting future ...
Behravesh, Arash, Spaul, Wilbur A.
core   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Analysis of wheel wear characteristics of high-speed train based on field data

open access: yesNihon Kikai Gakkai ronbunshu, 2019
A wheel/rail profile wear is a factor that affects the behavior of railway vehicles such as riding comfort, running stability, running safety and maintenance schedule.
Satoshi HARA   +2 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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