Results 81 to 90 of about 11,082,968 (347)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Evaluation of the CDOM Absorption Coefficient in the Arctic Seas Based on Sentinel-3 OLCI Data
Remote Sensing, 2020 Our work’s primary goal is to reveal the problematic issues related to estimates of the colored organic matter absorption coefficient in the northern seas from data of the Ocean and Land Color Instrument (OLCI) installed on the Sentinel-3 satellites, e.g.
Dmitry Glukhovets +6 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
A Simplified Method for Real-Time Prediction of Temperature in Mass Concrete at Early Age
Applied Sciences, 2020 According to the practice of temperature control in dam concrete, within a few days after a concrete block is poured, the temperature at the core of the concrete rises rapidly. The maximum temperature may still exceed the standard even under a relatively
Guo An +4 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Engineering ProceedingsAn EPA-SWMM model was used for the simulation of the intermittent water distribution system (WDS) of a small municipality in southern Italy. The model was compared with field data collected during an experimental campaign carried out in the intermittent ...
Aurora Gullotta, Alberto Campisano
doaj +1 more source
Embedded Sensors in Coastal Structures for On-Site Wave Impact Pressure Monitoring
IEEE Access, 2018 The climate change induces heavy storms that impact coastal environments. In order to predict such events or to adapt coastal structures in the future, it is desirable to be able to monitor the action of waves.
Franck Luthon +2 more
doaj +1 more source
Data Reduction Pipeline for the CHARIS Integral-Field Spectrograph I: Detector Readout Calibration and Data Cube Extraction [PDF]
, 2017 We present the data reduction pipeline for CHARIS, a high-contrast integral-field spectrograph for the Subaru Telescope. The pipeline constructs a ramp from the raw reads using the measured nonlinear pixel response, and reconstructs the data cube using ...
Brandt, Timothy D. +16 more
core +1 more source