Results 31 to 40 of about 1,059,681 (219)

Dynamic and thermal analysis of dust storm processes based on vertical observation data [PDF]

open access: yesNatural Hazards and Earth System Sciences
The Taklimakan Desert (TD) is a major dust-source region in East Asia, yet the dynamic and thermal processes associated with dust-storm development remain insufficiently understood from vertically resolved observations.
Y. Wang   +35 more
doaj   +1 more source

Indirect Reciprocity; A Field Experiment. [PDF]

open access: yesPLoS ONE, 2016
Indirect reciprocity involves cooperative acts towards strangers, either in response to their kindness to third parties (downstream) or after receiving kindness from others oneself (upstream).
Jacobien van Apeldoorn, Arthur Schram
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Characteristics of extreme precipitation and precipitation estimation under different return periods in the Pamir Plateau

open access: yesFrontiers in Earth Science
IntroductionAs the “Water Tower of Central Asia,” the Pamir Plateau is critical for regional water security. Research on its extreme precipitation is therefore vital for water resource assessment, hydrological modeling, and disaster risk planning ...
Shujuan Li   +29 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Potential Source Regions and Transportation Pathways of Reactive Gases at a Regional Background Site in Northwestern China

open access: yesAdvances in Meteorology, 2021
Reactive gases (O3, CO, NO2, and SO2) were collected hourly at the Akedala regional background station in northwestern China during September 2017 to August 2018.
Quanwei Zhao   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Spring snowmelt flood disasters in Altay, Northwest China: Spatio-temporal distribution and mechanisms

open access: yesJournal of Hydrology: Regional Studies
Study region: Altay region in Northwest China. Study focus: The frequency, intensity, and impacts of spring snowmelt flood disasters have changed significantly. However, there is still a limited understanding of snowmelt floods and their causes in Altay.
Dilinuer Tuoliewubieke   +7 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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