Results 51 to 60 of about 1,059,681 (219)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Integrated photovoltaic-agriculture systems enhance soil health in desert ecosystems: evidence from microbial biomass and nutrient synergies

Scientific Reports
This study systematically evaluated the effects of three typical desert restoration models in the Hobq Desert—the integrated photovoltaic-agriculture model (PV-Ag), the artificial shrub aerial seeding model (ASS), and the bare sand with photovoltaic ...
Mingjie Ma, Fan Yang, Xiannian Zheng, Xinghua Yang, Ali Mamtimin, Chenglong Zhou, Chaofan Li, Wen Huo, Xinqian Zheng, Tianhe Wang, Peng He, Qing Gong   +11 more
doaj   +1 more source

Technique of agrotechnical field experiment

Сельскохозяйственные машины и технологии, 2017
Application of modern technologies and innovative technical equipment at cultivation of grain-crops, including winter wheat, flax, clover and rape, causes actuality of carrying out the multivariable field test.
V. V. Golubev, A. V. Kudryavtsev, A. S. Firsov, M. A. Safonov   +3 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Interspecific interactions alter survival strategies of tree-shrub plants and hinder treeline ascent at alpine treelines in Southeastern Tibet: Evidence from13C and15N

Ecotoxicology and Environmental Safety
Nitrogen (N) and phosphorus (P) are pivotal nutrients that support species diversity in plant communities. However, in nutrient-poor alpine treeline ecosystems, the mechanisms through which interspecific interactions among treeline plants regulate ...
Ganggang Chen, Liangna Guo, Fangwei Fu, Bo Zhang, Yuzhuo Liu, Jietin Li, Yibo Zhang, Yi Li, Gengxin Zhang, Jiangrong Li   +9 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Elevational distribution patterns and drivers factors of fungal community diversity at different soil depths in the Abies georgei var. smithii forests on Sygera Mountains, southeastern Tibet, China

Frontiers in Microbiology
IntroductionSoil fungal communities play a crucial role in maintaining the ecological functions of alpine forest soil ecosystems. However, it is currently unclear how the distribution patterns of fungal communities in different soil layers of alpine ...
Bo Zhang, Bo Zhang, Bo Zhang, Bo Zhang, Sijie Zhu, Sijie Zhu, Sijie Zhu, Sijie Zhu, Jiangrong Li, Jiangrong Li, Jiangrong Li, Jiangrong Li, Jiangrong Li, Fangwei Fu, Fangwei Fu, Fangwei Fu, Fangwei Fu, Liangna Guo, Liangna Guo, Liangna Guo, Liangna Guo, Jieting Li, Jieting Li, Jieting Li, Jieting Li, Yibo Zhang, Yibo Zhang, Yibo Zhang, Yibo Zhang, Yuzhuo Liu, Yuzhuo Liu, Yuzhuo Liu, Yuzhuo Liu, Ganggang Chen, Ganggang Chen, Ganggang Chen, Ganggang Chen, Gengxin Zhang   +37 more
doaj   +1 more source