Results 71 to 80 of about 72,552 (260)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
A Note on Extended Genus Fields of Kummer Extensions of Global Rational Function Fields
We consider the generalization of the extended genus field of a prime degree cyclic Kummer extension of a global rational function field obtained by R. Clement in 1992 to general Kummer extensions.
Martha Rzedowski-Calderón +1 more
doaj +1 more source
Capitulation of the 2-ideal classes of type (2, 2, 2) of some quartic cyclic number fields
Let p≡3(mod4){p\equiv 3\pmod{4}} and l≡5(mod8){l\equiv 5\pmod{8}} be different primes such that pl=1{\frac{p}{l}=1} and 2p=pl4{\frac{2}{p}=\frac{p}{l}_{4}}. Put k=ℚ(l){k=\mathbb{Q}(\sqrt{l})}, and denote by ϵ its fundamental unit. Set K=k(-2pϵl){K=k(
Azizi Abdelmalek +3 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Nicely semiramified division algebras over Henselian fields
This paper deals with the structure of nicely semiramified valued division algebras. We prove that any defectless finite-dimensional central division algebra over a Henselian field E with an inertial maximal subfield and a totally ramified maximal ...
Karim Mounirh
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Equisetum arvense is an herbaceous perennial plant traditionally used in human medicine (i.e. for organic silicon supplementation). It is an approved basic substance with fungicidal properties under Article 23 of agricultural EU pesticide regulation (EC)
A. Taylor +7 more
doaj
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Thermal corrections in classically conformal models typically induce a strong first-order electroweak phase transition, thereby resulting in a stochastic gravitational background that could be detectable at gravitational wave observatories.
Luca Marzola +2 more
doaj +1 more source

