Results 91 to 100 of about 126,847 (331)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Deuterium Fractionation as an Evolutionary Probe in Massive Proto-stellar/cluster Cores

, 2011
Clouds of high infrared extinction are promising sites of massive star/cluster formation. A large number of cloud cores discovered in recent years allows investigation of possible evolutionary sequence among cores in early phases.
Aikawa, Battersby, Bergin, Beuther, Beuther, Beuther, Bottinelli, Calvet, Caselli, Caselli, Caselli, Ceccarelli, Chambers, Chen, Chen, Cortes, Crapsi, Crutcher, Crutcher, Egan, Friesen, Froebrich, Goodman, Guilloteau, Hosokawa, Huei-Ru Chen, Indebetouw, Kim, Lee, McKee, Mei-Yan Wang, Mestel, Miettinen, Molinari, Myers, Oliveira, Osorio, Peretto, Rathborne, Rathborne, Rathborne, Roberts, Sakai, Sanhueza, Sheng-Yuan Liu, Shepherd, Shepherd, Shepherd, Sridharan, Sridharan, Stark, Stark, Vastel, Vastel, Wang, Williams, Yu-Nung Su, Zhang   +57 more
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Factors affecting particle retention in thermal field-flow fractionation

Bulletin of the Chemical Society of Ethiopia, 2002
In this paper, we report a range of factors which affect the retention of colloidal particles in thermal field-flow fractionation (ThFFF). These results are observed among different sizes of polystyrene (PS) latex particles suspended in both aqueous and ...
Paul M. Shiundu, Stephen M. Munguti, Ben M. Wamalwa   +2 more
doaj  

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li, Dong‐Lin Liang, Li‐Ping Gao, Wei‐Wei Zhang, Wei Zhou, A. Ruhan, Bing Xu, Run‐Dong Cao, Kang Xiao, Cao Chen, Qi Shi, Xiao‐Ping Dong   +11 more
wiley   +1 more source

Characterization of seed nuclei in glucagon aggregation using light scattering methods and field-flow fractionation

Journal of Biological Engineering, 2008
Background Glucagon is a peptide hormone with many uses as a therapeutic agent, including the emergency treatment of hypoglycemia. Physical instability of glucagon in solution leads to problems with the manufacture, formulation, and delivery of this ...
Kirsch Lee E, Nguyen Lida T, Hoppe Cindy C, Wiencek John M   +3 more
doaj   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source

Treatment of Low Quality Water by Foam Fractionation [PDF]

, 1968
Project Number: A-015-ALAS Agreement Number: 14-01-0001-896 Project Duration: July 1, 1966 - June 30, 1967The removal of iron from Alaskan groundwaters by a foam fractionation technique has been shown to very effective.
Murphy, R. Sage
core  

Directly comparing coronal and solar wind elemental fractionation

, 2020
As the solar wind propagates through the heliosphere, dynamical processes irreversibly erase the signatures of the near-Sun heating and acceleration processes. The elemental fractionation of the solar wind should not change during transit however, making
Baker, D., Brooks, D. H., Owen, C. J., Stansby, D.   +3 more
core   +1 more source

Interaction between Molten Al‐Killed Mn–B Steel and Carbon‐Bonded MgO Refractories Based on Recyclates

Advanced Engineering Materials, EarlyView.
High‐temperature interactions between low‐sulfur Al‐killed Mn–B steel and MgO–C refractories (0 and 50 wt% recyclates) are studied via finger immersion tests (1600 °C). Surface‐active elements influence infiltration. MgO/CaS layer forms, along with spinel and calcium silicate.
Matheus Roberto Bellé, Lukas Neubert, Anton Yehorov, Till M. J. Stadtmüller, Christos G. Aneziris, Olena Volkova   +5 more
wiley   +1 more source