Results 61 to 70 of about 126,847 (331)

Isotope (¹⁴C and ¹³C) analysis of deep peat CO₂ using a passive sampling technique [PDF]

, 2009
We developed and tested a new method to collect CO₂ from the surface to deep layers of a peatland for radiocarbon analysis. The method comprises two components: i) a probe equipped with a hydrophobic filter that allows entry of ...
Garnett, M.H., Hardie, S.M.L.
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Separation and Detection of Escherichia coli and Saccharomyces cerevisiae Using a Microfluidic Device Integrated with an Optical Fibre

Biosensors, 2019
This paper describes the development of an integrated system using a dry film resistant (DFR) microfluidic channel consisting of pulsed field dielectrophoretic field-flow-fractionation (DEP-FFF) separation and optical detection.
Mohd Firdaus Kamuri, Zurina Zainal Abidin, Mohd Hanif Yaacob, Mohd Nizar Hamidon, Nurul Amziah Md Yunus, Suryani Kamarudin   +5 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Development of an advanced on-line position-specific stable carbon isotope system and application to methyl tert-butyl ether [PDF]

, 2009
We present an advanced system for on-line position-specific carbon isotope analysis. The main limitation of on-line intramolecular isotope ratio measurements has been that optimal pyrolytic fragments are obtained mostly at temperatures where the analyte ...
Abelson, Barrie, Barth, Benson, Coplen, Corso, Corso, Corso, Daly, Dempster, Dias, Elsner, Elsner, Fischer, Gray, Hall, Hall, Harrington, Hayes, Hirschorn, Huang, Hunkeler, Jasper, Jeffrey, Kolhatkar, Kuder, Mancini, Mariotti, Matthews, Meckenstock, Meier-Augenstein, Meier-Augenstein, Merritt, Miller, Monson, Morrison, O'Sullivan, Poulson, Richnow, Rosell, Sacks, Sano, Schmidt, Schmidt, Schüth, Slater, Slater, Slater, Smallwood, Somsamak, Somsamak, Vogler, Wang, Wolyniak, Wolyniak, Yamada, Zwank   +56 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Extracellular vesicle and particle isolation from human and murine cell lines, tissues, and bodily fluids

STAR Protocols, 2021
Summary: We developed a modified protocol, based on differential ultracentrifugation (dUC), to isolate extracellular vesicles and particles (specifically exomeres) (EVPs) from various human and murine sources, including cell lines, surgically resected ...
Linda Bojmar, Han Sang Kim, Gabriel C. Tobias, Fanny A. Pelissier Vatter, Serena Lucotti, Kofi Ennu Gyan, Candia M. Kenific, Zurong Wan, Kyung-A Kim, DooA Kim, Jonathan Hernandez, Virginia Pascual, Todd E. Heaton, Michael P. La Quaglia, David Kelsen, Tanya M. Trippett, David R. Jones, William R. Jarnagin, Irina R. Matei, Haiying Zhang, Ayuko Hoshino, David Lyden   +21 more
doaj   +1 more source

Internal fibre length concentration in a pressure screen [PDF]

, 2007
Localised axial consistency profiles within a pressure screen of a Pinus Radiata kraft pulp are reported. Axial Samples were also analysed using a Kajaani FS-200 to obtain fibre length distribution data.
Atkins, Martin John, Walmsley, Michael R.W., Weeds, Zuben   +2 more
core   +1 more source

Isospin fractionation in the nucleon emissions and fragment emissions in the intermediate energy heavy ion collisions

, 2003
The degree of isospin fractionation is measured by $(N/Z)_{n}$ / $(N/Z)_{N_{imf}}$, where $(N/Z)_{n}$ and $(N/Z)_{N_{imf}}$ are the saturated neutron-proton ratio of nucleon emissions (gas phase) and that of fragment emissions (liquid phase) in heavy ion
Aichelin, Aichelin, Alkahzov, Baran, Bertsch, Colonna, Danielewicz, Di Toro, Hang Liu, Jian-Ye Liu, Klakow, Kunde, Li, Li, Li, Li, Li, Liu, Liu, Liu, Miller, Pak, Pak, Pak, Pak, Rami, Reinhard, Sobotka, Sobotka, Tsang, Udo Schröder, Wada, Wen-Jun Guo, Westfall, Westfall, Xu, Yang, Yennello, Yennello, Yong Zhong Xing   +39 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source