Results 101 to 110 of about 3,670,404 (285)
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Nutrition-sensitive value chains: A guide for project design [PDF]
, 2019 A first-of-its-kind, this new Guide from IFAD presents practical, step-by-step guidance for shaping value chain projects to improve nutrition. The Guide highlights challenges and opportunities in establishing nutrition-sensitive value chains (NSVCs) and ...
International Fund for Agricultural Development
core
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
The Causal Fairness Field Guide: Perspectives From Social and Formal Sciences. [PDF]
Front Big Data, 2022 Carey AN, Wu X.
europepmc +1 more source
, 1978 1978 Men\u27s Track and Field Media Guide, George Fox ...
George Fox University Archives
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The American Biology Teacher, 2017 Insects and Other Arthropods of Tropical America . By Paul E. Hanson. Photographs by Kenji Nishida. 2016. Cornell University Press. (ISBN 9780801456947). 375 pages. Softcover. $37.95. If I were an extra-terrestrial visiting Earth for the first time, I would refer to it as “The Planet of the Insects”!
openaire +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Response to: "Electronic Field Guides and User Communities in the Eco-informatics Revolution"
Ecology and Society, 2006 John A. Burton
doaj +1 more source