Results 251 to 260 of about 10,222,885 (316)

Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues

Advanced Healthcare Materials, EarlyView.
Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman, Hadas Oved, Itay Gil, Amgad Marzook, Ester Sapir Baruch, Yahel Shechter, Assaf Shapira, Tal Dvir   +7 more
wiley   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Maize plasticity characterization through in-field 3D phenotyping​

, 2022
Serouart, Mario, Lopez Lozano, Raul, Beaumont, Maeva, Escale, Brigitte, de Solan, Benoit, Baret, Frederic   +5 more
openaire   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

Phenotyping the hidden half: combining UAV phenotyping and machine learning to predict barley root traits in the field. [PDF]

J Exp Bot
Alahmad S, Smith D, Katsikis C, Aldiss Z, Brunner SM, Meer SV, Meijer L, Heidariask B, Chenu K, Chapman S, Potgieter AB, Wasson A, Baraibar S, Godoy J, Moody D, Robinson H, Hickey LT.   +16 more
europepmc   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

Narrowing farmland biodiversity knowledge gaps with Digital Agriculture. [PDF]

NPJ Sustain Agric
Remelgado R, Beckmann M, Vítězslav M, Padulosi E, Perrone M, Vihervaara P, Marrs C, Eltner A, Rocchini D, Cord AF.   +9 more
europepmc   +1 more source

Integrated biotechnological and artificial intelligence innovations for plant improvement. [PDF]

Front Plant Sci
Wu H, Luo M, Liu Y, Yang J, Cao Y.
europepmc   +1 more source

The digital orchard: advanced data-driven technologies in apple breeding and genetic modification. [PDF]

Front Plant Sci
Abid F, Zhang Z, Farooque G, Zulqarnain RM, Rasheed J, Osman O, Alsubai S, Jamel L.   +7 more
europepmc   +1 more source