Results 151 to 160 of about 3,389,759 (261)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Occupational Exposure to Resorcinol and Thyroid-Disrupting Effects: Protocol for an Exploratory Field Study in French Hairdressers. [PDF]

JMIR Res Protoc
Radauceanu A, Cambrai-Erb A, Adet B, Nioule MI, Denis F, Pons R.   +5 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Insights into the Electronic and Structural Properties of Cellulose and Amylose: A Comparative Force Field Study. [PDF]

J Phys Chem B
Mohammadi E, Lemkul JA.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Evaluating Multi-Benefit Cover Crop Management Models for Citrus Sustainable Management: A Field Study from Central China. [PDF]

Plants (Basel)
Tang RB, Li LJ, Guo YH, Yuan R, Feng YT, Wang JC, Yu YC, Song HY, Zhang J, Wu D, Xiang GJ.   +10 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Effectiveness of Step Goal Personalization Strategies on Physical Activity in a Mobile Health App: A Field Study. [PDF]

JMIR Mhealth Uhealth
Liu X, Bijmolt THA, Leliveld MC, Noppers EH.   +3 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Demographic, behavioral, and ecological data from a long-term field study of wild baboons in Amboseli, Kenya. [PDF]

Sci Data
Southworth CA, Winans JC, Gordon JB, Learn NH, Wilber WA, Andreadis C, Andreasen G, Arandjelovic M, Campbell CR, Chege MN, Creighton MJA, Cromer CM, Debray R, Dickson CC, Ferretti P, George EM, Gesquiere LR, He S, Hey L, Jefferson EE, Kulahci IG, Lerch BA, Nonnamaker L, Rivas-González I, Tuliozi B, Webb SE, Alberts SC, Archie EA, Tung J.   +28 more
europepmc   +1 more source