Results 91 to 100 of about 295,686 (314)

Holographic Schwinger-Keldysh effective field theories

open access: yesJournal of High Energy Physics, 2019
We construct a holographic dual of the Schwinger-Keldysh effective action for the dissipative low-energy dynamics of relativistic charged matter at strong coupling in a fixed thermal background.
Jan de Boer   +2 more
doaj   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Gauge Theories and Holisms [PDF]

open access: yes, 2004
Those looking for holism in contemporary physics have focused their attention primarily on quantum entanglement. But some gauge theories arguably also manifest the related phenomenon of nonseparability.
Healey, Richard
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Perturbed conformal field theory, nonlinear integral equations and spectral problems [PDF]

open access: yes, 2000
This thesis is concerned with various aspects of perturbed conformal field theory and the methods used to calculate finite-size effects of integrable quantum field theories.
Dunning, Tania Clare   +2 more
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Higher Time-Derivative Theories from Space–Time Interchanged Integrable Field Theories [PDF]

open access: yes
We compare a relativistic and a nonrelativistic version of Ostrogradsky’s method for higher-time derivative theories extended to scalar field theories and consider as an alternative a multi-field variant.
Takano Taira   +8 more
core   +1 more source

Spin-charge separation for paired Dirac fermions in (1 + 1) dimensions

open access: yesJournal of High Energy Physics
We study Dirac fermions at finite density coupled to a complex pairing field assumed to obey scalar field theory with quartic self-repulsion. The bulk of our work develops the mathematics that elucidates the propagation of fermionic excitations in such ...
Laith H. Haddad
doaj   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

The viability of modified gravity theories [PDF]

open access: yes, 2009
PhDThis thesis studies the viability of classes of modified gravity (MG) theories based on generalisations of the Einstein-Hilbert action. Particular emphasis is given to f(R) theories in both the metric and Palatini formalisms, scalar-tensor theories ...
Uddin, Kotub
core  

Home - About - Disclaimer - Privacy