Results 81 to 90 of about 1,332,546 (338)
Advanced Science, EarlyView.In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong +11 more
wiley +1 more source
‘Going implicit’: using implicit measures in organizations [PDF]
, 2019 Implicit tests are increasingly being used and discussed in the field of Industrial-Organizational psychology. Despite their growing popularity, little is known about the types of implicit tests that exist, how they operationalize constructs, and how to ...
De Kock, François S. +2 more
core +1 more source
, 2015 Affects---emotions and moods---have an impact on cognitive activities and the working performance of individuals. Development tasks are undertaken through cognitive processes, yet software engineering research lacks theory on affects and their impact on ...
Abrahamsson, Pekka +2 more
core +2 more sources
Advanced Science, EarlyView.PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao +6 more
wiley +1 more source
Seeking sustainability leadership [PDF]
, 2015 This paper critiques mainstream leadership and leadership development approaches to help inform the emerging field of sustainability leadership.
Bendell, Jem, Little, Richard
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Advanced Science, EarlyView.The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang +15 more
wiley +1 more source
A Virtual Clinical Trial of Psychedelics to Treat Patients With Disorders of Consciousness
Advanced Science, EarlyView.Disorders of consciousness after severe brain injury are marked by reduced complexity of brain activity and limited treatment options. Using personalized whole‐brain models, this study shows that simulated lysergic acid diethylamide (LSD) and psilocybin shift patient brain dynamics closer to criticality.
Naji L.N. Alnagger +17 more
wiley +1 more source
From computers to cultivation: reconceptualizing evolutionary psychology. [PDF]
, 2014 Does evolutionary theorizing have a role in psychology? This is a more contentious issue than one might imagine, given that, as evolved creatures, the answer must surely be yes.
Bach-y-Rita +101 more
core +6 more sources
Advanced Science, EarlyView.Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao +36 more
wiley +1 more source
The personality systems framework: Current theory and development [PDF]
, 2015 The personality systems framework is a fieldwide outline for organizing the contemporary science of personality. I examine the theoretical impact of systems thinking on the discipline and, drawing on ideas from general systems theory, argue that ...
Mayer, John D.
core +2 more sources