Results 201 to 210 of about 681,925 (265)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

A non-invasive approach to measuring body dimensions of wildlife with camera traps: A felid field trial. [PDF]

Ecol Evol
Paton AJ, Brook BW, Buettel JC.
europepmc   +1 more source

Field Trial Validation

Field Trial ...
openaire   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Framing financial incentives to promote hypertension care among rural primary doctors in Shandong Province, China: study protocol of a randomized field trial. [PDF]

Health Econ Rev
Zhong Y, Fan P, Tan J, Maitland E, Nicholas S, Qiao Y, Kou D, Meng Z, Wang J.   +8 more
europepmc   +1 more source

Field Trial Design

Field Trial ...
openaire   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Results of a 6-Month Field Trial of a Transitional Intervention for Debilitating Hyperacusis. [PDF]

J Speech Lang Hear Res
Formby C, Cherri D, Secor CA, Armstrong S, Juneau R, Hutchison P, Eddins DA.   +6 more
europepmc   +1 more source

Effectiveness of multimedia education on the childbearing intention in one-child women: a field trial study. [PDF]

BMC Med Educ
Aghazadeh N, Jabbari Farooji S, Haghani S, Amini L.   +3 more
europepmc   +1 more source

Behavior change interventions to promote adoption of e-bike shared mobility in a rural area: evidence from a mixed-method field trial. [PDF]

Front Psychol
Wilson M, Whitmarsh L.
europepmc   +1 more source