Results 211 to 220 of about 9,510,506 (294)

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Field Trial Evaluation of the Diagnostic Accuracy of an Opisthorchis viverrini-Rapid Diagnostic Test (OV-RDT) for Opisthorchiasis in Northeast Thailand

Wongphutorn P, Worasith C, Khongsukwiwat K, Techasen A, Kopolrat KY, Loilome W, Namwat N, Pitaksakulrat O, Eamudomkarn C, Titapun A, Khuntikeo N, Futrakul S, Andrews RH, Taylor-Robinson SD, Sithithaworn P.   +14 more
europepmc   +1 more source

A user-friendly NoSQL framework for managing agricultural field trial data. [PDF]

Sci Rep
Wu SH, Mueller TA.
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Randomised controlled field trial to assess the safety and efficacy of a killed autologous vaccine against Streptococcus dysgalactiae subspecies dysgalactiae in a sheep flock. [PDF]

Vet Rec
Angell JW, Ahmed N, Jackson LP, Kasiora K, Ballingall K, Duncan JS.   +5 more
europepmc   +1 more source

The beagle and the field trials

, 1900
openaire   +2 more sources

Founding Editorial: Neuro‐Drug Discovery

Neuro-Drug Discovery, EarlyView.
Wenbin Li
wiley   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Two decades long-term field trial data on fertilization, tillage, and crop rotation focusing on soil microbes. [PDF]

Sci Data
Raab M, Schütz L, Sommermann L, Babin D, Kampouris I, Francioli D, Grosch R, Neumann G, Deubel A, Geistlinger J, Bade K, Rozhon W.   +11 more
europepmc   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source