Results 91 to 100 of about 85,792 (305)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A study on the fire fighting system in UiTM Shah Alam / Mohd Alfi Syahrin Ibrahim

open access: yes, 2013
This dissertation completed was mainly motivated by the desire to provide a good management for fire fighting system in University Technology Mara ( Uitm ) Shah Alam.
Ibrahim, Mohd Alfi Syahrin
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Feasibility of Protecting Residential Structures from Wildfires using a Fixed Exterior Fire Fighting System

open access: yes, 2020
A performance-based design approach was applied to quantify wildfire exposures for residences and to design an automatic fixed fire-fighting compressed foam system for protecting such ...
Parrow, Dylan M.   +2 more
core  

Organization of modernization of control system of fire-fighting in the twentieth century [PDF]

open access: yes, 2013
Организация модернизации системы управления пожарным делом на Урале, изменение форм и методов управления.The organization of modernization of control system of fire-fighting in the Urals, change of forms and methods of ...
Корник, В. Н., Cornick, V. N.
core  

A Teleoperated Fire Fighting Robot with a Multi-Sensor System for Navigation Purposes

open access: yes, 2022
S.371-376The development of a multi-sensor system with navigation purposes for a teleoperated fire fighting robot is described in this paper. The robot system consists of a tracked vehicle which pulls the fire fighting equipment to the scene of fire.
Hägele, M., Rust, H., Schraft, R.D.
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Fire-fighting Vehicles

open access: yes, 2021
This bachelor's thesis deals with the technology of fire-fighting vehicles. The first section of the thesis describes the historical development of the vehicles and their use in the Czech Republic and around the world.
Šamánek, Jan
core   +1 more source

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