Results 81 to 90 of about 85,792 (305)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

PIC (Peripheral Interface Controller) based Automatic Fire Fighting System Using Fuzzy Logic Control [PDF]

open access: yes, 2009
PIC (peripheral Interface Controller) based controlling system is widely used and very popular all over the world. In this system, automatic fire fighting system will be implemented with PIC by using fuzzy logic control.
Thi, Nandar Kay
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Practical aspects of automatic fire alarm system in hotels and similar establishments for catering purposes

open access: yes, 2015
Rad daje pregled, komentare i prijedloge rješenja za nekoliko, u praksi najčešće susretanih problema i nedostataka sustava dojave požara, odnosno općenito protupožarnih sustava u hotelskim i srodnim objektima u Hrvatskoj. Razmatra se funkcionalni odnos i
Prpić, Emil, Emil Prpić
core  

A new approach towards Teleoperated Fire Fighting

open access: yes, 2022
S.250-255Many attempts concerning teleoperated fire fighting were made without much success so far. In this paper a new approach towards teleoperated fire fighting is presented that bases on experiences of the past.
Rust, H., Schraft, R.D.
core  

Preparing Retro Arcade Fighting Game Asset Design

open access: yes, 2023
Games are increasingly popular in Indonesia because of the many things that make them exciting, such as esports. The Fighting Game genre is one that contains a fight between two characters in a place or arena with the aim of depleting the opponent's HP ...
Waksito, Alan Zulfikar   +3 more
core   +1 more source

Effects on the Operational Level of War: Fighting Power and the Problem of Military Effectiveness

open access: yesObrana a Strategie, 2010
War as a complex adaptive system indicates that effects can have both systematic and accidental causes. In war there are identifiable cause-and-effect relationships, and phenomena we cannot explain based on analytical rationality.
Zoltán JOBBÁGY
doaj  

The urgent issues of land conservation in Ukraine

open access: yesZemleustrìj, Kadastr ì Monìtorìng Zemelʹ, 2023
The article addresses the issue of land conservation at war and post-war reconstruction. The complex understanding of land conservation issues at the current conditions is an important stage of their resolving in the future.
O. Malashevska, М. Malashevskyi
doaj  

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