Results 41 to 50 of about 7,286,252 (205)

Virtual corpses, figural sections and resonant fields

open access: yes, 2011
The ‘figural section’ is one of the most potent but under used forms of architectural communication. It enables slices, extrusions, fragments and surfaces of buildings to become the media of the non-expressive and deadpan.
Griffiths, S., Sean Griffiths
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

PSYNDEX Tests Review für RFFT - Ruff Figural Fluency Test - deutsche Fassung

open access: yes, 2006
This is a PSYNDEX Tests Review of RFFT - Ruff Figural Fluency Test - deutsche Fassung. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Melchers, Peter, Feldmann, Barbara
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Bachelor Thesis - Andrea Trachsel_Development of a test to measure the figural-spatial intelligence

open access: yes, 2023
In this thesis the test to measure the figural-spatial intelligence developing by the Department Cognitive Psychology: Judgment, Decision Making, Action in the University of Hagen will be examined in regards to gender differences in test scores.
Alexander Nowak   +2 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Flowchart of participants who performed the Ruff Figural Fluency Test.

open access: yes, 2015
Mean (SD) follow-up time between measurement 1 and 2 was 2.8 (0.5) years and between measurement 2 and 3 2.7 (0.5) years. Abbreviations: RFFT, Ruff Figural Fluency Test.
Ron T. Gansevoort (111233)   +5 more
core   +1 more source

Perfil cognitivo de estudiantes con bajo rendimiento intelectual. Asociaciones entre inteligencia y creatividad

open access: yesActualidades Investigativas en Educación
El estudiantado con bajo rendimiento intelectual se caracteriza por presentar alteraciones en distintas áreas del funcionamiento cognitivo, académico y conductual.
Blanca Ivet Chávez Soto   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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