Results 71 to 80 of about 3,623 (226)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Improvements and future challenges for the research infrastructure in the field “Measuring cognitive ability” [PDF]
The assessment of cognitive abilities is critical in large-scale survey studies that aim at elucidating the longitudinal interplay between the individual’s cognitive potential and socio-economic variables.
Elsbeth Stern, Roland H. Grabner
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Trinocular stereovision using figural continuity, dealing with curved objects [PDF]
A method to build a dense and reliable 3-D description of a scene from three digital images by means of passive stereovision is presented. This method uses figural continuity to improve the results of a previously developed algorithm.
Faugeras, O. D., Vaillant, R.
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Tracing a Route and Finding a Shortcut: The Working Memory, Motivational, and Personality Factors Involved [PDF]
, 2018 Wayfinding (WF) is the ability to move around efficiently and find the way from a starting point to a destination. It is a component of spatial navigation, a coordinate and goal-directed movement of one\u2019s self through the environment. In the present
Allen +56 more
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FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Do age and gender make a difference in the relationship between intellectual styles and abilities? [PDF]
, 2010 This article reports two studies that aim at further distinguishing intellectual styles from abilities by taking into account the confounding effects of age and gender on the relationship between these two constructs.
Zhang, LF
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FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Does working memory training have to be adaptive? [PDF]
, 2015 This study tested the common assumption that, to be most effective, working memory (WM) training should be adaptive (i.e., task difficulty is adjusted to individual performance). Indirect evidence for this assumption stems from studies comparing adaptive
Eschen, A., Von Bastian, Claudia C.
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